Protein Alignment Nep5 and Nep5

DIOPT Version :10

• Sequence 1: NP_733186.2
• Gene: Nep5 / 43255
• FlyBaseID: FBgn0039478
• Length: 882
• Species: Drosophila melanogaster
• Sequence 2: XP_061503273.1
• Gene: Nep5 / 1273520
• VectorBaseID: AGAMI1_014349
• Length: 834
• Species: Anopheles gambiae
• Alignment Length: 885
• Identity: 418/885 - (47%)
• Similarity: 568/885 - (64%)
• Gaps: 65/885 - (7%)

  Fly     8 RIWTTGNINHGFFGDNLQQQPLPLQRLQTPGNLSLLSAPIRANGSGNGNATANGHGQNSATESAN 72
            |||||.: ||                                       .|..|| ::..:...:
Mosquito     5 RIWTTDS-NH---------------------------------------RTDYGH-ESEKSSVTH 28

  Fly    73 GKQLPYEPISPNLIGIQSKFRRSYYHKVVLGGLLALVIILLIAIIVISLGLKKSSSICRSKECLR 137
            ...:|....:|.||||||:|||.||||.::..||.::.||.||||||:..|.....||.|.:|||
Mosquito    29 PHTVPPPAGNPYLIGIQSRFRRRYYHKSIVLFLLLVIFILTIAIIVIACLLHFPPEICHSADCLR 93

  Fly   138 TAASLIYAMDEQTDPCEDFYQFTCGRWANEHPRPDSVTSNDWFRERQAHIMRVVREFLRSNITKS 202
            :||:|.::||...||||||||:.||.|.:||||||:..|.|||.||||.|:|.:|.:|::|.:..
Mosquito    94 SAAALKHSMDLTVDPCEDFYQYACGNWEDEHPRPDTYVSFDWFSERQAKILRNIRHYLQANSSAL 158

  Fly   203 EPEAVGKAKTMYRACMDTKLLDKRDLEPLINYLLRFGLPVLPSALNLTLGSGSKYATEAANVKYN 267
            :|:.|.:|:|||.||::...:|:....|:..||.:|.||..||.||:|.|..|  || .....::
Mosquito   159 DPKPVVQARTMYAACLNLTAMDRLGYGPVFKYLKQFQLPPYPSLLNVTEGPAS--AT-FQGYGFD 220

  Fly   268 WLQSIVSIKQHLTMDLIIGFDVFPDPFNRTINRIALGTPETDSAFPFNNDDSHKMLRKIHR---K 329
            |::|:..|||.|.||:.||.||:|||.:|..||:.|||||:.|..|||.|    :||.|.|   :
Mosquito   221 WVKSLAKIKQLLGMDIFIGLDVYPDPRHRDYNRLVLGTPESGSDLPFNTD----ILRHIRRGRTR 281

  Fly   330 TIFMQNSDDEDDSEDDRESEEEEAAKQTSTGMTAYLHYVRKVIEKYLLYVDPNVNQEEATLGITE 394
            ...|.::|||.|.|.|  .||.|.|......:|||..::..|::..:...||.:..|........
Mosquito   282 RKLMVSADDEADGESD--GEEVEDADDEVGPLTAYKKFMIGVMKLLVNSTDPTIKVESFNAQFER 344

  Fly   395 LVKQGVRVARKVHEFKEEAENMTKPSKNPAD-----DIVYITLQDLQNQTDKNIAPK-TLPIWVR 453
            .....|:.:..:.:|..||||.:: |.|..|     ||||.|:.||||.||.::||| .||||.|
Mosquito   345 AATIVVQFSDSISKFNREAENASR-STNVEDRLNLQDIVYYTVADLQNITDTHLAPKDPLPIWER 408

  Fly   454 YMELILKGTRHAGNIQMT-QNLTIITSQADITYLQNIVEYLDDTPASHIESYLFLSTIEELVLHT 517
            .:..:.:|...|   |:. |:..|:||.||:.||:.:|:||..||.:|||.|::.:.:|||:|||
Mosquito   409 LLASVFEGIPEA---QLNLQDELILTSNADLLYLKLLVDYLAVTPLAHIELYIWWTVVEELILHT 470

  Fly   518 SSSMRLLHSEYMRVAIGTEGSTPRSLYCANGVNSLLGMAVSYVLADADFTKEKLPKVERMLSDIR 582
            :..:|.|:.:|.:....::|.:.|:|||...||.||||||||.::..:||::..|:|:.||..||
Mosquito   471 TLEVRKLYYDYYKSIAPSDGFSSRTLYCTGTVNRLLGMAVSYAISSDNFTRDTKPRVQDMLRYIR 535

  Fly   583 RSFDRLVKSTSWMDAATKRKTIQKSAEMKSFIGFPPWLRNASVLNAYYEGAEVNASTHLENLMDF 647
            .:|:.||:.|:|||..||:.|::||..|:|.||||.|:.:...|..:|.|.:||.||||||:|..
Mosquito   536 TAFEGLVRDTTWMDWPTKQSTLRKSQAMRSLIGFPDWILDHRELEQHYSGLQVNESTHLENMMQE 600

  Fly   648 VHWQMMDKLNEMDKPEPIGWATSPSNVNAFHTFQSNAITVPIAILQYPFYDLGLEALNYGSIGTI 712
            |..:.:.||....:...:.|.|.|:|||||||||.||||:||||||||||.|||||||||::|||
Mosquito   601 VQRKNIIKLRRWRQKHELSWETLPTNVNAFHTFQENAITIPIAILQYPFYHLGLEALNYGALGTI 665

  Fly   713 LGHELTHGFDDSGRRFDRAGNMVEWWSNRTIDEYVNRTECFVEQYSRYHLADIDEYIDGELTLGE 777
            ||||||||||||||:||:.||:.:||::||:.||||||:|||.|||||::.:.|:||||.|||||
Mosquito   666 LGHELTHGFDDSGRQFDKDGNLAQWWTDRTVQEYVNRTKCFVSQYSRYYIPEADDYIDGLLTLGE 730

  Fly   778 NIADNGGMREAFYAYRLYVKEVGRERSKLPGLEHYSHEQLFFISFGNLWCETYTPAASRYALTDS 842
            |||||||:||||.||:||||..|:: ..|||.|||:||||||||:||:|||::|.||::..|.||
Mosquito   731 NIADNGGVREAFRAYQLYVKNGGKD-PLLPGFEHYTHEQLFFISYGNIWCESHTQAAAKAYLDDS 794

  Fly   843 HCPGQMRLRGVLSNSEEFARTFKCARGTPMNPDQPKCRIW 882
            ||||:.||:|||:||.||::||.|..||.|||.:.|||||
Mosquito   795 HCPGKFRLKGVLTNSPEFSQTFGCKPGTEMNPGKDKCRIW 834

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep5	NP_733186.2	M13	151..880	CDD:341056	367/738 (50%)
Nep5	XP_061503273.1	None