Protein Alignment Nep5 and Eef1ece2

DIOPT Version :10

• Sequence 1: NP_733186.2
• Gene: Nep5 / 43255
• FlyBaseID: FBgn0039478
• Length: 882
• Species: Drosophila melanogaster
• Sequence 2: NP_808810.1
• Gene: Eef1ece2 / 110599584
• MGIID: 6121518
• Length: 910
• Species: Mus musculus
• Alignment Length: 831
• Identity: 233/831 - (28%)
• Similarity: 397/831 - (47%)
• Gaps: 144/831 - (17%)

  Fly    86 IGIQSKFRRSY-YH---KVVLGGL-LALVIILLIAIIVISLGLKKSSSICRSKECLRTAASLIYA 145
            :|.|.:.|:.: .|   ::||.|| |.|..:||..::.:.:....:.|.|.::.|:|.|..::.:
Mouse   190 VGFQKRTRQLFGSHTQLELVLAGLILVLAALLLGCLVALWVHRDPAHSTCVTEACIRVAGKILES 254

  Fly   146 MDEQTDPCEDFYQFTCGRWANEHPRPDS----VTSNDWFRERQAHIMRVVREFLRSNITKSEPEA 206
            :|....||:|||||:||.|...:|.|:.    .|.|..:.:.||    :::..|.:....|..||
Mouse   255 LDRGVSPCQDFYQFSCGGWIRRNPLPNGRSRWNTFNSLWDQNQA----ILKHLLENTTFNSSSEA 315

  Fly   207 VGKAKTMYRACMDTKLLDKRDLEPLINYLLRFGLPVLPSALNLTLGSGSKYATEAANVKYNWLQS 271
            ..|.::.|.:|:.::.::|...:||.:.:.:.|                     ..|:...|.:
Mouse   316 ERKTRSFYLSCLQSERIEKLGAKPLRDLIDKIG---------------------GWNITGPWDE- 358

  Fly   272 IVSIKQHLTMDLIIGFDVFPDPFNRTINRIALGTPETDSAFPF-------NNDDSHKMLRKIHRK 329
                                |.|...:..:|    .|..|.||       ::..|:..:.::.:.
Mouse   359 --------------------DSFMDVLKAVA----GTYRATPFFTVYVSADSKSSNSNIIQVDQS 399

  Fly   330 TIFMQNSDDEDDSEDDRESEEEEAAKQTSTGMTAYLHYVRKVIEKYLLYVDPNVNQEEATLGITE 394
            .:|:.:.    |...:|.:.|:.        :||||.|:.::  ..||...|...:|:
Mouse   400 GLFLPSR----DYYLNRTANEKV--------LTAYLDYMVEL--GVLLGGQPTSTREQ------- 443

  Fly   395 LVKQGVRVARKVHEFKEEAENMTKPSKNPAD-DIVY--ITLQDLQNQTDKNIAPKTLPIWVRYME 456
                    .::|.|.:.:..|:|.|.....| :.:|  :::.:||     .:||..  .|:.::.
Mouse   444 --------MQQVLELEIQLANITVPQDQRRDEEKIYHKMSISELQ-----ALAPAV--DWLEFLS 493

  Fly   457 LILKGTRHAGNIQMTQNLTIITSQADITYLQNIVEYLDDTPASHIESYLFLSTIEELVLHTSSSM 521
            .:|      ..:::..:..::....:  |||.:.|.::.|..|.:.:||    |..||..|:||:
Mouse   494 FLL------SPLELGDSEPVVVYGTE--YLQQVSELINRTEPSILNNYL----IWNLVQKTTSSL 546

  Fly   522 ---------RLLHSEYMRVAIGTEGS-TPRSLYCANGVNSLLGMAVSYVLADADFTKEKLPKVER 576
                     :||.:.|     ||:.| |||...|.:..:..||.|:..:...|.|.::.....|.
Mouse   547 DQRFETAQEKLLETLY-----GTKKSCTPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEG 606

  Fly   577 MLSDIRRSFDRLVKSTSWMDAATKRKTIQKSAEMKSFIGFPPWLRNASVLNAYYEGAEVNASTHL 641
            |:::||.:|:..:....|||..|:....:|:..:...||||.::.....|:..|:|.||:..:..
Mouse   607 MINEIRSAFEETLGDLVWMDEKTRLAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEVSEDSFF 671

  Fly   642 ENLMDFVHWQ---MMDKLNEMDKPEPIGWATSPSNVNAFHTFQSNAITVPIAILQYPFYDLG-LE 702
            :|:::..::.   |.|:|.:  .|....|:.:|..|||::....|.|..|..|||.|||... .:
Mouse   672 QNMLNLYNFSAKVMADQLRK--PPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYAHNHPK 734

  Fly   703 ALNYGSIGTILGHELTHGFDDSGRRFDRAGNMVEWWSNRTIDEYVNRTECFVEQYSRYHLADIDE 767
            |||:|.||.::||||||.|||.||.:|:.||:..||.|.::..:.|.|.|..||||:|.:.  .|
Mouse   735 ALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLTAFQNHTACMEEQYSQYQVN--GE 797

  Fly   768 YIDGELTLGENIADNGGMREAFYAYRLYVKEVGRERSKLPGLEHYSHEQLFFISFGNLWCETYTP 832
            .::|..|||||||||||::.|:.||:.::::.|.|: .||.:...:| ||||:.|..:||...||
Mouse   798 RLNGLQTLGENIADNGGLKAAYNAYKAWLRKHGEEQ-PLPAVGLTNH-QLFFVGFAQVWCSVRTP 860

  Fly   833 AASRYAL-TDSHCPGQMRLRGVLSNSEEFARTFKCARGTPMNPDQPKCRIW 882
            .:|...| ||.|.|.:.|:.|.||||.:|.|.|.|..|:||||.| .|.:|
Mouse   861 ESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQ-LCEVW 910

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep5	NP_733186.2	M13	151..880	CDD:341056	213/757 (28%)
Eef1ece2	NP_808810.1	UbiG	46..>128	CDD:441829
		M13	259..908	CDD:341056	213/758 (28%)