Protein Alignment Nep5 and kel

DIOPT Version :10

• Sequence 1: NP_733186.2
• Gene: Nep5 / 43255
• FlyBaseID: FBgn0039478
• Length: 882
• Species: Drosophila melanogaster
• Sequence 2: XP_068070210.1
• Gene: kel / 101882278
• ZFINID: ZDB-GENE-110411-118
• Length: 793
• Species: Danio rerio
• Alignment Length: 849
• Identity: 158/849 - (18%)
• Similarity: 274/849 - (32%)
• Gaps: 270/849 - (31%)

  Fly   114 IAIIVISLGL-----------------KKSSSICRSKECLRTAASLIYAMDEQTDPCEDFYQFTC 161
            :::...:|||                 |.::.:|.|..|:|.:.....|||..:.|| |::.|.|
Zfish    79 VSLFATALGLGIYSHLQKTADPWKSKWKSAAPLCLSPACIRASEHFSVAMDPFSRPC-DYFLFAC 142

  Fly   162 GRW--------------ANEHPR------------PDSVTSND----WFRERQAHIMRVVREFLR 196
            |..              .|:|..            .|..:.:|    .|.:||..::..::|.|
Zfish   143 GAGGSSTNRDRQRVKGEVNKHSEVRTRGLIEMRRGTDGWSKSDGQLKTFPDRQTALLTAIKEIL- 206

  Fly   197 SNITKSEPEAVG------KAKTMYRACMDTKLLDKRDLEPLINYLLRFGLPVLPSALNLTLGSGS 255
                ::..|||.      |||..:::||:.:..:|...||.:..|.:.|
Zfish   207 ----EAPDEAVSMGAAEQKAKNFFKSCMNAESREKMGSEPFLTLLQQLG---------------- 251

  Fly   256 KYATEAANVKYNWLQSIVSIKQHLTMDLIIGFDVFPDPFNRTINRIALGTPETDSAFPFNNDDSH 320
            .:|....     |.|:                     .||.|: .:.:|...|   |||.|
Zfish   252 GWAVSGV-----WNQT---------------------DFNSTL-ALLMGQYST---FPFFN---- 282

  Fly   321 KMLRKIHRKTIFMQNSDDEDDSEDDRE-----------SEEEEAAKQTSTGMTAYLHYVRKVIEK 374
                      :::.....|:.|..:|.           ..|..:..|.:...|.||........:
Zfish   283 ----------VYVGPEPSEEQSASNRHYIQIDEPHFQFPIEWNSKTQKAKANTRYLRPFYSACGQ 337

  Fly   375 YL---------------LYVDPNVNQEEATLGITELVKQGVRVARKVHEFKEEAENMTKPSKNPA 424
            ||               |:|..:.....||..:...:.|.:...|
Zfish   338 YLVLLGVPSDRTTQHCGLFVSLSTTLAVATFPLPYRLSQKLLYRR-------------------- 382

  Fly   425 DDIVYITLQDLQNQTDKNIAPKTLPIWVRYME------LILKGTRHAGNIQMTQNLTIITSQADI 483
                 .|:|:||     .:||..  .|:..::      ||.|     .:|.:..||..|...:..
Zfish   383 -----TTIQELQ-----TLAPAV--DWLACLQATFQPLLISK-----SDIVLVHNLPYIIHMSKT 430

  Fly   484 TYLQNIVEYLDDTPASHIESYLFLSTIEELVLHTSSSMRLLHSEYMRVAIGTEGSTPRSLYCA-- 546
            .:|..:...|..|  ..:.:|:..|.::.|:....|....:...| .:|.|.....|....|.
Zfish   431 IHLWQVQHELMGT--GPLNTYMIFSLLQTLIPALDSRFFQIMRNY-SIATGDTQEMPHWWRCVQQ 492

  Fly   547 --NGVNSLLGMAVSYVLADADFTKEKLPKVERMLSDIRRSFDRLVKSTSWMDAATKRKTIQKSAE 609
              .|.::||..|:.        .|....:.|.::.|:..|..:.:...||.|.......:.|...
Zfish   493 TERGFDTLLSHAIR--------EKHAQKEAEELIQDVYSSLKKKLTDLSWRDEKESDFILNKINS 549

  Fly   610 MKSFIGFPPWLRNASVLNAYYEGAEVNASTHLENLMDFVHWQMMDKLNEMDKPEPIGWATSPSNV 674
            :...|.......:.:.||..||...:|......|.:..:      .|.:..:...:...|....:
Zfish   550 LNPRISTNTNNLSYTELNHLYEKVILNEEDFFSNYLQIL------LLEQKSRARLLSLGTQTEGL 608

  Fly   675 NAFHTFQSNAITVPIAILQYPFYDLGL-EALNYGSIGTILGHELTH-GFDDSGRRFDRAGN---- 733
            :.......|.|.||:.:...||:.... .|||||::|:::..:|.| ...|.   :.:|.|
Zfish   609 SMTPFISGNDIIVPVGMFVSPFFHSSYPRALNYGTLGSLMAKDLLHLLLPDI---YTKAKNPETE 670

  Fly   734 -MVEW-----------WSNRTIDEYVNRTECFVEQYSRYHLADIDEYIDGELTLGENIADNGGMR 786
             :..|           |.:........:.|.:| |||...:| :|.|   :::....:||
Zfish   671 SLCVWSHYLSVTKGPGWGDAFYLPSSKQQEVWV-QYSALQVA-LDAY---KMSFKRYLAD----- 725

  Fly   787 EAFYAYRLYVKEVGRERSKLPGLEHYSHEQLFFISFGNLWCET-----YTPAASRYALT-----D 841
                             |.|||   :|:..||..||..:.|:|     :.|....:.:|     .
Zfish   726 -----------------SSLPG---FSYVHLFLSSFTKVTCDTDAYREFMPLEPSFLVTVLCSNS 770

  Fly   842 SHCP 845
            ..||
Zfish   771 GLCP 774

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep5	NP_733186.2	M13	151..880	CDD:341056	147/795 (18%)
kel	XP_068070210.1	GluZincin	133..>654	CDD:472708	116/640 (18%)
		GluZincin	617..>755	CDD:472708	40/170 (24%)