DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment RYa-R and TACR1

DIOPT Version :9

Sequence 1:NP_001287552.1 Gene:RYa-R / 43253 FlyBaseID:FBgn0004842 Length:518 Species:Drosophila melanogaster
Sequence 2:NP_001049.1 Gene:TACR1 / 6869 HGNCID:11526 Length:407 Species:Homo sapiens


Alignment Length:334 Identity:112/334 - (33%)
Similarity:166/334 - (49%) Gaps:53/334 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly    98 MWSSAYFKIIVYMLYIPIFIFALIGNGTVCYIVYSTPRMRTVTNYFIASLAIGDILMSFFCVPSS 162
            :|::||..|:|         .:::||..|.:|:.:..|||||||||:.:||..:..|:.|....:
Human    34 LWAAAYTVIVV---------TSVVGNVVVMWIILAHKRMRTVTNYFLVNLAFAEASMAAFNTVVN 89

  Fly   163 FISLFILNYWPFGLALCHFVNYSQAVSVLVSAYTLVAISIDRYIAIMWPLKPRITKRYATFIIAG 227
            | :..:.|.|.:||..|.|.|:....:|..|.|::.|::.|||:||:.||:||::......:|..
Human    90 F-TYAVHNEWYYGLFYCKFHNFFPIAAVFASIYSMTAVAFDRYMAIIHPLQPRLSATATKVVICV 153

  Fly   228 VWFIALATALPIPIVSGLDIPMSPWHTKCEKYICREMWPSRTQEYY---YTLSLFALQFVVPLGV 289
            :|.:||..|.|....|..:       |...:.:|...||....:.|   |.:.:..|.:.:||.|
Human   154 IWVLALLLAFPQGYYSTTE-------TMPSRVVCMIEWPEHPNKIYEKVYHICVTVLIYFLPLLV 211

  Fly   290 LIFTYARITIRVWAKRPPGEAETNRDQRMARSKRKMVKMMLTVVIVFTCCWLPFNILQLLLNDEE 354
            :.:.|..:.|.:||...||:: ::|......:|||:||||:.||..|..|||||:|..|      
Human   212 IGYAYTVVGITLWASEIPGDS-SDRYHEQVSAKRKVVKMMIVVVCTFAICWLPFHIFFL------ 269

  Fly   355 FAHWDPLPY-------------VWFAFHWLAMSHCCYNPIIYCYMNARFRSGFVQLMHRMPGLRR 406
                  |||             |:.|..|||||...|||||||.:|.|||.||....       |
Human   270 ------LPYINPDLYLKKFIQQVYLAIMWLAMSSTMYNPIIYCCLNDRFRLGFKHAF-------R 321

  Fly   407 WCCLRSVGD 415
            .|...|.||
Human   322 CCPFISAGD 330

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
RYa-RNP_001287552.1 7tm_4 113..>234 CDD:304433 41/120 (34%)
7tm_1 122..383 CDD:278431 93/276 (34%)
TACR1NP_001049.1 7tmA_NK1R 33..316 CDD:320668 105/311 (34%)
TM helix 1 35..59 CDD:320668 9/32 (28%)
TM helix 2 68..90 CDD:320668 7/21 (33%)
TM helix 3 106..128 CDD:320668 6/21 (29%)
TM helix 4 149..165 CDD:320668 5/15 (33%)
TM helix 5 194..217 CDD:320668 5/22 (23%)
TM helix 6 247..269 CDD:320668 13/21 (62%)
TM helix 7 284..309 CDD:320668 14/24 (58%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 364..407
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D314830at33208
OrthoFinder 1 1.000 - - FOG0000620
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.920

Return to query results.
Submit another query.