Protein Alignment RYa-R and TACR2

DIOPT Version :9

• Sequence 1: NP_001287552.1
• Gene: RYa-R / 43253
• FlyBaseID: FBgn0004842
• Length: 518
• Species: Drosophila melanogaster
• Sequence 2: NP_001048.2
• Gene: TACR2 / 6865
• HGNCID: 11527
• Length: 398
• Species: Homo sapiens
• Alignment Length: 378
• Identity: 128/378 - (33%)
• Similarity: 197/378 - (52%)
• Gaps: 44/378 - (11%)

  Fly    71 SGLQFETYNITVMMNFSCDDYDLLSEDMWSSAYFKIIVYMLYIPIFIFALIGNGTVCYIVYSTPR 135
            ||.:..|..||.   ||...:.|.   :|::||..::         :.|:.||..|.:|:.:..|
Human    14 SGPESNTTGITA---FSMPSWQLA---LWATAYLALV---------LVAVTGNAIVIWIILAHRR 63

  Fly   136 MRTVTNYFIASLAIGDILMSFFCVPSSFISLFILNYWPFGLALCHFVNYSQAVSVLVSAYTLVAI 200
            |||||||||.:||:.|:.|:.|....:|: ....|.|.||.|.|:|.|.....::.||.|::.||
Human    64 MRTVTNYFIVNLALADLCMAAFNAAFNFV-YASHNIWYFGRAFCYFQNLFPITAMFVSIYSMTAI 127

  Fly   201 SIDRYIAIMWPLKPRITKRYATFIIAGVWFIALATALPIPIVSGLDIPMSPWHTKCEKYICREMW 265
            :.|||:||:.|.:||::......:|||:|.:|||.|.|....|  .:.|....|||.     ..|
Human   128 AADRYMAIVHPFQPRLSAPSTKAVIAGIWLVALALASPQCFYS--TVTMDQGATKCV-----VAW 185

  Fly   266 P----SRTQEYYYTLSLFALQFVVPLGVLIFTYARITIRVWAKRPPGEAETNRDQRMARSKRKMV 326
            |    .:|...|: |.:.||.:.:||.|:...|:.|.:.:|.:..||......:.|..::.:|.|
Human   186 PEDSGGKTLLLYH-LVVIALIYFLPLAVMFVAYSVIGLTLWRRAVPGHQAHGANLRHLQAMKKFV 249

  Fly   327 KMMLTVVIVFTCCWLPFNILQLL--LNDEEFAHWDPLPYVWFAFHWLAMSHCCYNPIIYCYMNAR 389
            |.|:.||:.|..||||:::..:|  ..::.:.| ..:..|:.|..|||||...|||||||.:|.|
Human   250 KTMVLVVLTFAICWLPYHLYFILGSFQEDIYCH-KFIQQVYLALFWLAMSSTMYNPIIYCCLNHR 313

  Fly   390 FRSGFVQLMHRMPGLRRWCC---LRSVGDRMNAT-SGEMTTKYHR-HVGDALF 437
            ||||| :|..|       ||   ..:..|::..| :..::|:.:| |..:.||
Human   314 FRSGF-RLAFR-------CCPWVTPTKEDKLELTPTTSLSTRVNRCHTKETLF 358

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RYa-R	NP_001287552.1	7tm_4	113..>234	CDD:304433	47/120 (39%)
		7tm_1	122..383	CDD:278431	95/266 (36%)
TACR2	NP_001048.2	7tm_4	42..>168	CDD:304433	51/135 (38%)
		7tm_1	50..307	CDD:278431	95/266 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D314830at33208
OrthoFinder	1	1.000	-	-		FOG0000620
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.920