Protein Alignment RYa-R and sstr3

DIOPT Version :10

• Sequence 1: NP_001287552.1
• Gene: RYa-R / 43253
• FlyBaseID: FBgn0004842
• Length: 518
• Species: Drosophila melanogaster
• Sequence 2: XP_695365.1
• Gene: sstr3 / 566989
• ZFINID: ZDB-GENE-061009-35
• Length: 480
• Species: Danio rerio
• Alignment Length: 410
• Identity: 102/410 - (24%)
• Similarity: 176/410 - (42%)
• Gaps: 83/410 - (20%)

  Fly   106 IIVYMLYIPIFIFALIGNGTVCYIVYSTPRMRTVTNYFIASLAIGDIL----MSFFCVPSSFISL 166
            |::.::||.:.|..|.||..|.:||....:..:|||.:|.:|||.|.|    :.|..|.::
Zfish    58 ILIPLIYIIVCIVGLGGNSLVIHIVLHYSKTESVTNIYILNLAIADELFMLGLPFLAVQNA---- 118

  Fly   167 FILNYWPFGLALCHFVNYSQAVSVLVSAYTLVAISIDRYIAIMWPL------KPRITKRYATFII 225
              ::.||||...|..|.....::...|.:.|..:|||||:|::.|:      :|::.|.    :.
Zfish   119 --MHSWPFGSFTCRLVMTVDGINQFTSIFCLTVMSIDRYLAVVHPIRSSKWRRPQVAKA----VN 177

  Fly   226 AGVWFIALATALPIPIVSGLDIPMSPWHTKCEKYICREMWPSRTQEYYYTLSLF--ALQFVVPLG 288
            ..:|.::....||:.|.:.:         :.|..||..:||.....:.....::  .:.|..||.
Zfish   178 GTIWAVSFLVVLPVVIFASV---------QREGGICNIIWPKPANVWAAAFIIYTSTVGFFFPLL 233

  Fly   289 VLIFTYARITIRVWAKRPPGEAETNRDQRMARSKRKMVKMMLTVVIVFTCCWLPF---NILQLL- 349
            |:...|..|.|::   |..|:.......:..:|:||:.:|::.||.||..||:||   ||:.|:
Zfish   234 VICMCYLLIVIKI---RSSGKKVHATSTKRRKSERKVTRMVVIVVAVFVFCWMPFYALNIINLVE 295

  Fly   350 -LNDEEFAHWDPLPYVWFAFHWLAMSHCCYNPIIYCYMNARFRSGFVQLMHR------------- 400
             |.||      |.....|.. .|:.::.|.|||:|.:::..|:.||.:.:.|
Zfish   296 SLRDE------PQGLHLFVV-VLSYANSCANPIVYGFLSDNFKRGFRKALCRSSRRVENHEPTEQ 353

  Fly   401 -----------MPGLRRWCCLRSVGDRMNATSGEMTTKYHRHVGDALFRKPKIC--IRNGSSTSS 452
                       ||   |....|:|.|.    ..|...:|...|.:    ..:||  .:||:.:..
Zfish   354 QQHQEERRRVLMP---RESLRRAVRDE----EDEEEEEYREEVTE----MTEICRITQNGNGSGQ 407

  Fly   453 QSNEHIHHLHQRSSKATSDI 472
            ..:.....|.:.|....|::
Zfish   408 PESTRALFLERPSGTGVSEV 427

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RYa-R	NP_001287552.1	7tmA_PR4-like	106..394	CDD:320514	83/304 (27%)
		TM helix 1	107..133	CDD:320514	9/25 (36%)
		TM helix 2	140..165	CDD:320514	10/28 (36%)
		TM helix 3	179..209	CDD:320514	10/29 (34%)
		TM helix 4	220..241	CDD:320514	3/20 (15%)
		TM helix 5	271..300	CDD:320514	6/30 (20%)
		TM helix 6	320..350	CDD:320514	15/34 (44%)
		TM helix 7	362..387	CDD:320514	7/24 (29%)
sstr3	XP_695365.1	7tmA_SSTR3	58..334	CDD:320638	83/304 (27%)
		TM helix 1	59..85	CDD:320638	9/25 (36%)
		TM helix 2	92..118	CDD:320638	10/25 (40%)
		TM helix 3	129..159	CDD:320638	10/29 (34%)
		TM helix 4	171..193	CDD:320638	4/25 (16%)
		TM helix 5	216..245	CDD:320638	6/28 (21%)
		TM helix 6	262..292	CDD:320638	14/29 (48%)
		TM helix 7	302..327	CDD:320638	7/25 (28%)