DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment RYa-R and LOC561565

DIOPT Version :9

Sequence 1:	NP_001287552.1	Gene:	RYa-R / 43253	FlyBaseID:	FBgn0004842	Length:	518	Species:	Drosophila melanogaster
Sequence 2:	XP_021332202.1	Gene:	LOC561565 / 561565	-ID:	-	Length:	461	Species:	Danio rerio

Alignment Length:	389	Identity:	126/389 - (32%)
Similarity:	192/389 - (49%)	Gaps:	64/389 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    79 NITVMMNFSCDDYDLLSEDMWSSAYFKIIVYMLYIPIFIFALIGNGTVCYIVYSTPRMRTVTNYF 143
            |||.:        |....:.:.||.| |:.|:|   |||..::|||.||:||..:..||||||.|
Zfish    40 NITYV--------DFYLHEPFVSAIF-IVSYLL---IFIVCMMGNGVVCFIVLRSKNMRTVTNLF 92

  Fly   144 IASLAIGDILMSFFCVPSSFISLFILNYWPFGLALCHFVNYSQAVSVLVSAYTLVAISIDRYIAI 208
            |.:|||.|:|:..||:|::.:. .|:..||||..:|......|.:||..|.:|||||::||:..|
Zfish    93 ILNLAISDLLVGIFCMPTTLVD-NIITGWPFGSLVCKLSGMVQGISVSASVFTLVAIAVDRFRCI 156

  Fly   209 MWPLKPRITKRYATFIIAGVWFIALATALPIPIV------SGLDIPMSPWHTKCEKYICREMWPS 267
            ::|.|.::|...:|.||..:|.:|::...|..::      ..:.|.:|..:|....|.|||.||:
Zfish   157 VYPFKQKLTISTSTLIIIIIWVLAISIMCPSGVMLQVTKEHRVSILLSDGNTTQPFYWCRENWPN 221

  Fly   268 RTQEYYYTLSLFALQFVVPLGVLIFTYARITIRVWAKRPPG----------------EAETNRDQ 316
            :.....||..|||..::.||.:::..||||.|.::....|.                :......|
Zfish   222 QEMRKIYTTVLFANIYLAPLTLIVIMYARIGITLFKTSMPAPVSQVGTSGSGSGSGKQCRYESRQ 286

  Fly   317 RMARSKRKMVKMMLTVVIVFTCCWLPFNILQLLLND----EEFAHWDPLPYVWFAFHWLAMSHCC 377
            .::|.|::::||:|.|.::|...|||...| ::|:|    .|..|.....|.:...||||..:..
Zfish   287 LVSRKKKRVIKMLLVVALLFILSWLPLWAL-MMLSDYASLSERQHRVINIYFYPLAHWLAFCNSS 350

  Fly   378 YNPIIYCYMNARFRSGF-----VQLMHRMPGLRRWCCLRSVGDRMNATSGEMTTKYHRHVGDAL 436
            .|||||.:.|..||.||     :||           |        :..||...|..||..|:|:
Zfish   351 VNPIIYGFFNENFRKGFKAAFKLQL-----------C--------SGHSGNRRTYSHRLQGNAV 395

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RYa-R	NP_001287552.1	7tm_4	113..>234	CDD:304433	52/120 (43%)
RYa-R	NP_001287552.1	7tm_1	122..383	CDD:278431	96/286 (34%)
LOC561565	XP_021332202.1	7tm_GPCRs	55..367	CDD:333717	109/317 (34%)
		TM helix 1	57..81	CDD:320095	14/27 (52%)
		TM helix 2	90..112	CDD:320095	11/21 (52%)
		TM helix 3	128..150	CDD:320095	9/21 (43%)
		TM helix 4	171..187	CDD:320095	4/15 (27%)
		TM helix 5	226..249	CDD:320095	7/22 (32%)
		TM helix 6	293..318	CDD:320095	9/25 (36%)
		TM helix 7	335..360	CDD:320095	10/24 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910