DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RYa-R and TkR86C

DIOPT Version :9

Sequence 1:	NP_001287552.1	Gene:	RYa-R / 43253	FlyBaseID:	FBgn0004842	Length:	518	Species:	Drosophila melanogaster
Sequence 2:	NP_001097741.1	Gene:	TkR86C / 41286	FlyBaseID:	FBgn0004841	Length:	555	Species:	Drosophila melanogaster

Alignment Length:	455	Identity:	133/455 - (29%)
Similarity:	216/455 - (47%)	Gaps:	72/455 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    68 TTLSGLQFETYNITVMMNFSCDDYDLL-----SEDMWSSAYF-------------KIIVYMLYIP 114
            |||.|....| .:..:::...|:.|.|     ::|..:...|             |.|..:::..
  Fly    29 TTLLGSLNRT-EVVSLLSSIIDNRDNLESINEAKDFLTECLFPSPTRPYELPWEQKTIWAIIFGL 92

  Fly   115 IFIFALIGNGTVCYIVYSTPRMRTVTNYFIASLAIGDILMSFF-CVPSSFISLFILNY-WPFGLA 177
            :...|:.|||.|.:||.....||||||||:.:|:|.|:|||.. ||   |..:|:||. ||||..
  Fly    93 MMFVAIAGNGIVLWIVTGHRSMRTVTNYFLLNLSIADLLMSSLNCV---FNFIFMLNSDWPFGSI 154

  Fly   178 LCHFVNYSQAVSVLVSAYTLVAISIDRYIAIMWPLKPRITKRYATFIIAGVWFIALATALPIPIV 242
            .|...|:...|:|..|.:||||||.||||||:.|||.|.::|....|:..:|  ||:..|..|.:
  Fly   155 YCTINNFVANVTVSTSVFTLVAISFDRYIAIVHPLKRRTSRRKVRIILVLIW--ALSCVLSAPCL 217

  Fly   243 SGLDIPMSPWHTKCEKYICREMW-----PSRTQEYYYTLSLFALQFVVPLGVLIFTYARITIRVW 302
            ....|....::....:.:|..||     |:...:|.|.|.:..|.:.:|:.|::..|:.:...:|
  Fly   218 LYSSIMTKHYYNGKSRTVCFMMWPDGRYPTSMADYAYNLIILVLTYGIPMIVMLICYSLMGRVLW 282

  Fly   303 AKRPPGEAETNRDQRMARSKRKMVKMMLTVVIVFTCCWLPFNILQL-LLNDEEFAHWDPLPYVWF 366
            ..|..|| .|:|.....:||||:|:|.:.:|.:|..||||:::..: ..::.:.|....:.:::.
  Fly   283 GSRSIGE-NTDRQMESMKSKRKVVRMFIAIVSIFAICWLPYHLFFIYAYHNNQVASTKYVQHMYL 346

  Fly   367 AFHWLAMSHCCYNPIIYCYMNARFRSGFVQLMHRMPGLRRWCCLRSVGDRMNATSGEMTTKYHRH 431
            .|:|||||:...||:||.:||.|||..|.:::       ..||:.....|.::....:|.|
  Fly   347 GFYWLAMSNAMVNPLIYYWMNKRFRMYFQRII-------CCCCVGLTRHRFDSPKSRLTNK---- 400

  Fly   432 VGDALFRKPKICIRNGSSTSSQSNEHIHHLHQRSSKATSDIFASEPIIVRRDVTTAVAVISKNKT 496
                          |.|:..::....:.|....||..|:.              |.:||:::..|
  Fly   401 --------------NSSNRHTRGGYTVAHSLPNSSPPTTQ--------------TLLAVLAQTLT 437

Fly 497 496
Fly 438 437

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RYa-R	NP_001287552.1	7tm_4	113..>234	CDD:304433	56/122 (46%)
RYa-R	NP_001287552.1	7tm_1	122..383	CDD:278431	97/268 (36%)
TkR86C	NP_001097741.1	7tm_4	92..376	CDD:304433	106/289 (37%)
TkR86C	NP_001097741.1	7tm_1	100..363	CDD:278431	97/268 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D314830at33208
OrthoFinder	1	1.000	-	-		FOG0000620
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24238
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	4.020