Protein Alignment RYa-R and Lkr

DIOPT Version :10

• Sequence 1: NP_001287552.1
• Gene: RYa-R / 43253
• FlyBaseID: FBgn0004842
• Length: 518
• Species: Drosophila melanogaster
• Sequence 2: NP_647968.3
• Gene: Lkr / 38622
• FlyBaseID: FBgn0035610
• Length: 542
• Species: Drosophila melanogaster
• Alignment Length: 478
• Identity: 149/478 - (31%)
• Similarity: 223/478 - (46%)
• Gaps: 87/478 - (18%)

  Fly   107 IVYMLYIPIFIFALIGNGTVCYIVYSTPRMRTVTNYFIASLAIGDILMSFFCVPSSFISLFILNY 171
            ::.:.|..|.|.|:|||..|.::|.:|.:||||||.:||:||..|:::..||:|..| ...:|..
  Fly    37 LLSIFYGGISIVAVIGNTLVIWVVATTRQMRTVTNMYIANLAFADVIIGLFCIPFQF-QAALLQS 100

  Fly   172 WPFGLALCHFVNYSQAVSVLVSAYTLVAISIDRYIAIMWPLKPRITKRYATFIIAGVWFIALATA 236
            |.....:|.|..:.||:||.||.:||.||:|||:.||:.||:.|.||..:.|||.|:|.:||..|
  Fly   101 WNLPWFMCSFCPFVQALSVNVSVFTLTAIAIDRHRAIINPLRARPTKFVSKFIIGGIWMLALLFA 165

  Fly   237 LPIPIVSGLDIPMSPWHTKCEKY-----IC--REMWPSRTQEYYYTLSLFALQFVVPLGVLIFTY 294
            :|..|...::.....:....|.|     .|  :.:...:.|.:.|||..  :|::||..|:.|.|
  Fly   166 VPFAIAFRVEELTERFRENNETYNVTRPFCMNKNLSDDQLQSFRYTLVF--VQYLVPFCVISFVY 228

  Fly   295 ARITIRVWAKRPPGEAETNRDQRMARSKRKMVKMMLTVVIVFTCCWLPFNILQLL------LNDE 353
            .::.:|:|..|.||.|:.:||..:.::|:|::||::.|||:|..||||..:..:|      :||.
  Fly   229 IQMAVRLWGTRAPGNAQDSRDITLLKNKKKVIKMLIIVVIIFGLCWLPLQLYNILYVTIPEINDY 293

  Fly   354 EFAHWDPLPYVWFAFHWLAMSHCCYNPIIYCYMNARFRSGFVQ--------------------LM 398
            .|     :..|||...|||||:.||||.||...|.:|:..|.:                    .|
  Fly   294 HF-----ISIVWFCCDWLAMSNSCYNPFIYGIYNEKFKREFNKRFAACFCKFKTSMDAHERTFSM 353

  Fly   399 H-RMPGLRRWCCLRSVGDRMN----ATSGEMTTKYHRHVGDALFRKPKI-------CIRNGSSTS 451
            | |...:|......|:..|.|    |..|....|...|:       |::       .|.||||..
  Fly   354 HTRASSIRSTYANSSMRIRSNLFGPARGGVNNGKPGLHM-------PRVHGSGANSGIYNGSSGQ 411

  Fly   452 SQSNEHIHHLHQRSSKATSDIFASEPIIVRRDVTTA----------------------VAVISKN 494
            :.:....||.||  |..|   ||:.|.:....|..|                      ||::...
  Fly   412 NNNVNGQHHQHQ--SVVT---FAATPGVSAPGVGVAMPPWRRNNFKPLHPNVIECEDDVALMELP 471

  Fly   495 KTDSPVRRSGSSGGTEANIRSTE 517
            .|..|.....|..|.:..:.|.|
  Fly   472 STTPPSEELASGAGVQLALLSRE 494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RYa-R	NP_001287552.1	7tmA_PR4-like	106..394	CDD:320514	112/299 (37%)
		TM helix 1	107..133	CDD:320514	9/25 (36%)
		TM helix 2	140..165	CDD:320514	11/24 (46%)
		TM helix 3	179..209	CDD:320514	16/29 (55%)
		TM helix 4	220..241	CDD:320514	9/20 (45%)
		TM helix 5	271..300	CDD:320514	9/28 (32%)
		TM helix 6	320..350	CDD:320514	13/35 (37%)
		TM helix 7	362..387	CDD:320514	14/24 (58%)
Lkr	NP_647968.3	7tmA_leucokinin-like	36..329	CDD:320515	112/299 (37%)
		TM helix 1	37..63	CDD:320515	9/25 (36%)
		TM helix 2	70..95	CDD:320515	11/25 (44%)
		TM helix 3	108..138	CDD:320515	16/29 (55%)
		TM helix 4	149..170	CDD:320515	9/20 (45%)
		TM helix 5	205..234	CDD:320515	10/30 (33%)
		TM helix 6	254..284	CDD:320515	12/29 (41%)
		TM helix 7	297..322	CDD:320515	14/24 (58%)