DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RYa-R and CCKLR-17D3

DIOPT Version :9

Sequence 1:	NP_001287552.1	Gene:	RYa-R / 43253	FlyBaseID:	FBgn0004842	Length:	518	Species:	Drosophila melanogaster
Sequence 2:	NP_001097023.1	Gene:	CCKLR-17D3 / 32864	FlyBaseID:	FBgn0030954	Length:	584	Species:	Drosophila melanogaster

Alignment Length:	526	Identity:	138/526 - (26%)
Similarity:	199/526 - (37%)	Gaps:	171/526 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 NYQEG-------------------YFIRPDPASLIYNTTALPADDEGSNYGYGSTTTLSGLQFET 77
            ||:||                   |...|..|..|.:....|.:..|:    |.|.:|:|....:
  Fly     3 NYEEGDADQAAMAAAAAYRALLDYYANAPSAAGHIVSLNVAPYNGTGN----GGTVSLAGNATSS 63

  Fly    78 YNITVMMNFSCDDY------DLLSEDMW-----------------SSAYFKIIVYML--YIPIFI 117
            |.     :...|.|      ||::|..:                 ||....:.|:::  |..|.:
  Fly    64 YG-----DDDRDGYMDTEPSDLVTELAFSLGTSSSPSPSSTPASSSSTSTGMPVWLIPSYSMILL 123

  Fly   118 FALIGNGTVCYIVYSTPRMRTVTNYFIASLAIGDILMSFFCVPSSFISLFILNYWPFGLALCHFV 182
            ||::||..|...:....||||:||.|:.:|||.|:|:...|:|.:.:...:.|: .||..||...
  Fly   124 FAVLGNLLVISTLVQNRRMRTITNVFLLNLAISDMLLGVLCMPVTLVGTLLRNF-IFGEFLCKLF 187

  Fly   183 NYSQAVSVLVSAYTLVAISIDRYIAIMWPLKPRI--TKRYATFIIAGVWFIALATALPIPIVSGL 245
            .:|||.||.||::||||||.:||.||..||:.|.  |..:|..||..:|...:....||.:.|.|
  Fly   188 QFSQAASVAVSSWTLVAISCERYYAICHPLRSRSWQTISHAYKIIGFIWLGGILCMTPIAVFSQL 252

  Fly   246 DIPMS-PWHTKCEKYICREMWPSRTQEYYYTLSLFALQFVVPLGVLIFTYARITIRVW------- 302
             ||.| |.:.|     |||.||.:..|.:|.:.|..|..|:||.||...|..||..::
  Fly   253 -IPTSRPGYCK-----CREFWPDQGYELFYNILLDFLLLVLPLLVLCVAYILITRTLYVGMAKDS 311

  Fly   303 ------------------AKRP--------------------------------PGEAETN---- 313
                              |..|                                .|...||
  Fly   312 GRILQQSLPVSATTAGGSAPNPGTSSSSNCILVLTATAVYNENSNNNNGNSEGSAGGGSTNMATT 376

  Fly   314 ----------------------------------------RDQRMARSKRKMVKMMLTVVIVFTC 338
                                                    .:.:...||:::|||:..:|:.|..
  Fly   377 TLTTRPTAPTVITTTTTTTVTLAKTSSPSIRVHDAALRRSNEAKTLESKKRVVKMLFVLVLEFFI 441

  Fly   339 CWLP---FNILQLLLNDEEFAHWDPLPYVWFAF-HWLAMSHCCYNPIIYCYMNARFRSGFVQLMH 399
            ||.|   .|.:.:|:....:.:.|   |...:| ..||.|..|.|||.||:|||.||..||....
  Fly   442 CWTPLYVINTMVMLIGPVVYEYVD---YTAISFLQLLAYSSSCCNPITYCFMNASFRRAFVDTFK 503

  Fly   400 RMPGLR 405
            .:|..|
  Fly   504 GLPWRR 509

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RYa-R	NP_001287552.1	7tm_4	113..>234	CDD:304433	50/122 (41%)
RYa-R	NP_001287552.1	7tm_1	122..383	CDD:278431	100/368 (27%)
CCKLR-17D3	NP_001097023.1	7tm_4	120..>244	CDD:304433	50/124 (40%)
CCKLR-17D3	NP_001097023.1	7tm_1	128..487	CDD:278431	100/368 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45449362
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24238
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940