Protein Alignment RYa-R and npr-7

DIOPT Version :10

• Sequence 1: NP_001287552.1
• Gene: RYa-R / 43253
• FlyBaseID: FBgn0004842
• Length: 518
• Species: Drosophila melanogaster
• Sequence 2: NP_509570.3
• Gene: npr-7 / 185321
• WormBaseID: WBGene00018067
• Length: 380
• Species: Caenorhabditis elegans
• Alignment Length: 424
• Identity: 103/424 - (24%)
• Similarity: 185/424 - (43%)
• Gaps: 86/424 - (20%)

  Fly    79 NITVMMNFSCDDYDLLSEDMWSSAYFKIIVYMLYIPIFIFALIGNGTVCYIVYSTPRMRTVTNYF 143
            |:|   :|.| :|..:.    ...:.|.::.:.|..:...:|:||..|..||.....|:||||.|
 Worm     6 NLT---DFQC-EYPAID----IGIHMKTLLAVGYGLVGALSLVGNLAVLLIVICRREMQTVTNIF 62

  Fly   144 IASLAIGDILMSFFCVPSSFISLFILNYWPFGLALCHFVNYSQAVSVLVSAYTLVAISIDRYIAI 208
            |:|::..|::::.|.:.::.:: :....|.||..:|:.|:..|.:|::....||.|:::|||..:
 Worm    63 ISSVSAADLVITSFSLWATPLA-YYQRVWHFGKYMCYMVSIIQGLSLMWVPLTLAAVALDRYSLV 126

  Fly   209 MWPLKPRITKRYATFIIAGVWFIALATALP-IPIVSGLDIPMSPWHTKCEKYICREMWPSRTQEY 272
            ..|.:..::|:....||||:|....|...| |.:|..:| ...|.|      .|.|.|....|.|
 Worm   127 ASPFRQPMSKKTCLLIIAGIWMGGFAVLSPMIRMVDFVD-SYGPCH------FCLESWDHDKQHY 184

  Fly   273 --YYTLSLFALQFVVPLGVLIFTYARITIRVWAKRPPGEAETNRDQRM-----------ARSKRK 324
              :|.||:..::..:||.::...:.||.:.:       ..:|.:.|.:           .|.|::
 Worm   185 RLFYGLSVLVIRSAIPLVLISLCHWRIAVIL-------NTQTKKFQTLRSASTVTQSTDIRRKQR 242

  Fly   325 MVKMMLTVVIVFTCCWLPF---NILQLLLNDEEFAHWDPLP-----YVWFAFHWLAMSHCCYNPI 381
            :..::|.:|::|....||.   |:||.|:...:..   |:|     :::|..||.||:....||:
 Worm   243 LQTLLLAMVVIFAVSSLPLDLSNVLQDLIVVYQVR---PVPDNVRHFIFFFCHWTAMAGTLLNPL 304

  Fly   382 IYCYMNARFRSGFVQLMHRMPGLRRWCCLRSVGDRMNATSGEMTTKYHRHVGDALFRKPKICIRN 446
            :|.|.|..||.                       ::....|||.       |...|::....|.:
 Worm   305 VYAYYNENFRR-----------------------QIQTCFGEMR-------GQGEFKRGLYSIVS 339

  Fly   447 G----SSTSSQSNEHIHHLH----QRSSKATSDI 472
            |    ..|....:|..||..    :.::..|.||
 Worm   340 GRYSYRETFRADDEENHHRQNTRIELANNQTGDI 373

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RYa-R	NP_001287552.1	7tmA_PR4-like	106..394	CDD:320514	83/309 (27%)
		TM helix 1	107..133	CDD:320514	7/25 (28%)
		TM helix 2	140..165	CDD:320514	7/24 (29%)
		TM helix 3	179..209	CDD:320514	10/29 (34%)
		TM helix 4	220..241	CDD:320514	8/21 (38%)
		TM helix 5	271..300	CDD:320514	8/30 (27%)
		TM helix 6	320..350	CDD:320514	10/32 (31%)
		TM helix 7	362..387	CDD:320514	10/29 (34%)
npr-7	NP_509570.3	7tmA_NPYR-like	25..317	CDD:320331	83/332 (25%)
		TM helix 1	26..52	CDD:320331	7/25 (28%)
		TM helix 2	59..84	CDD:320331	7/24 (29%)
		TM helix 3	97..127	CDD:320331	10/29 (34%)
		TM helix 4	138..159	CDD:320331	7/20 (35%)
		TM helix 5	185..214	CDD:320331	7/28 (25%)
		TM helix 6	238..268	CDD:320331	8/29 (28%)
		TM helix 7	285..310	CDD:320331	9/24 (38%)