DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RYa-R and srsx-9

DIOPT Version :9

Sequence 1:	NP_001287552.1	Gene:	RYa-R / 43253	FlyBaseID:	FBgn0004842	Length:	518	Species:	Drosophila melanogaster
Sequence 2:	NP_504336.2	Gene:	srsx-9 / 185000	WormBaseID:	WBGene00017845	Length:	293	Species:	Caenorhabditis elegans

Alignment Length:	325	Identity:	63/325 - (19%)
Similarity:	125/325 - (38%)	Gaps:	86/325 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   103 YFKIIVYMLYIPIFIFALIGNGTVCYIVYSTPRMRTVTNYFIASLAIGDILMSFFCVPSSFI--- 164
            ||.::..:|:|   :|..|||....::::...:::|.|:          :|..|.|...:|.
Worm     9 YFVVVYKILFI---VFGTIGNSLFIHLIFKRKQLQTRTS----------VLQCFQCSFQTFCLFG 60

  Fly   165 SLF--ILN----------YWPFGLALCHFVNYSQAVSVLVSAYTLVAISIDRYIAIMWPLKPRIT 217
            :||  |:|          :|.....:  |...:|.:.:||       |.||..|.:.:|...| :
Worm    61 TLFDGIINLGHSFNRRECFWQISFYI--FFQAAQGIIMLV-------IVIDILIFVKYPFFYR-S 115

  Fly   218 KRYATFIIAGVWFIALATALPIPIVSGLDIPMSPWHTKCEKYICREMWPSRTQEYYYT-LSLFAL 281
            ..::|::|        ||:.|:              ..|...:....:.|..:|...| :.:|.|
Worm   116 ISFSTYLI--------ATSFPV--------------LMCSTVVTAYSYYSVNEEVINTCVPMFVL 158

  Fly   282 Q---------FVVPLGVLIFTYARITIRVW-AKRPPGEAETNRDQRMARSKRKMVKMMLTVVIVF 336
            .         |::.:.:::.....|.||.: .|:..|..          :..|.:|.:...|.:|
Worm   159 SNQASTVYKLFIIFINIIVTVVYVILIRTFHLKKQTGNL----------TSLKTIKGLQFSVSIF 213

  Fly   337 TCCWLPFNILQLL-LNDEEFAHWDPLPYVWFAFHW-LAMSHCCYNPIIYCYMNARFRSGFVQLMH 399
            ...|....|:.|| |.....:.|:.:.|:..:|.. |:.|:..|   :..:.:..:|..|..:.:
Worm   214 IFTWFFSQIIALLILKQYSSSSWENIIYMHNSFLMSLSYSNTFY---VTLWKSKEYRKQFKNIWY 275

Fly 400 399
Worm 276 275

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RYa-R	NP_001287552.1	7tm_4	113..>234	CDD:304433	28/135 (21%)
RYa-R	NP_001287552.1	7tm_1	122..383	CDD:278431	55/288 (19%)
srsx-9	NP_504336.2	TM helix 1	16..36	CDD:341315	6/22 (27%)
		7TM_GPCR_Srsx	19..274	CDD:255903	60/312 (19%)
		TM helix 2	43..66	CDD:341315	7/32 (22%)
		TM helix 3	78..108	CDD:341315	9/38 (24%)
		TM helix 4	118..135	CDD:341315	6/38 (16%)
		TM helix 5	160..183	CDD:341315	1/22 (5%)
		TM helix 6	201..227	CDD:341315	7/25 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910