Protein Alignment RYa-R and Gpr83

DIOPT Version :9

• Sequence 1: NP_001287552.1
• Gene: RYa-R / 43253
• FlyBaseID: FBgn0004842
• Length: 518
• Species: Drosophila melanogaster
• Sequence 2: XP_030099918.1
• Gene: Gpr83 / 14608
• MGIID: 95712
• Length: 480
• Species: Mus musculus
• Alignment Length: 541
• Identity: 131/541 - (24%)
• Similarity: 210/541 - (38%)
• Gaps: 161/541 - (29%)

  Fly    20 AHQQPMLRNEDDNYQEGYFIRPDPASLIYNTTALPADDEGSNYGYGSTTTLSGLQ---FETYNIT 81
            |.:||.:..|..: .|.....|:.:|..:           :||.:.......|.:   .|:.|.|
Mouse    17 ATEQPQVVTEHPS-MEAALTGPNASSHFW-----------ANYTFSDWQNFVGRRRYGAESQNPT 69

  Fly    82 VMMNFSCDDYDLLSEDMWSSAYFKIIVYMLYIPIFIFALIGNGTVCYIVYSTPRMRTVTNYFIAS 146
            |                      |.::.:.|....:|:|.||..||::::...||.:.|:.||.:
Mouse    70 V----------------------KALLIVAYSFTIVFSLFGNVLVCHVIFKNQRMHSATSLFIVN 112

  Fly   147 LAIGDILMSFFCVPSSFISLFILNYWPFGLALCHFVNYSQAVSVLVSAYTLVAISIDRY------ 205
            ||:.||:::....|.:.:. |:.:.|.||..:||...::|..|:.|||.||.||::||:
Mouse   113 LAVADIMITLLNTPFTLVR-FVNSTWVFGKGMCHVSRFAQYCSLHVSALTLTAIAVDRHQGLELQ 176

  Fly   206 ---------------------------------------------------IAIMWPLKPRITKR 219
                                                               ..||.||||||:..
Mouse   177 KMVRPRGDGGELRSPSVTFVPSSLCPALFTCKRPWDFQESQSLHDTLFPPLEVIMHPLKPRISIT 241

  Fly   220 YATFIIAGVWFIALATALPIPIVSGLDIPMSPWHTKCEKY------------ICREMWPSRTQEY 272
            .....||.:|.:|...:||              |..|:|.            :|...:|.....:
Mouse   242 KGVIYIAVIWVMATFFSLP--------------HAICQKLFTFKYSEDIVRSLCLPDFPEPADLF 292

  Fly   273 --YYTLSLFALQFVVPLGVLIFTYARITIRVWAKRPPGEAETNRDQRMARSKRKMVKMMLTVVIV 335
              |..|:.|.|.:::||.::...|||:..::|.....|:..|.:...:.|.|:..|||::.||::
Mouse   293 WKYLDLATFILLYLLPLFIISVAYARVAKKLWLCNTIGDVTTEQYLALRRKKKTTVKMLVLVVVL 357

  Fly   336 FTCCWLPFNILQLLLNDEEFAHWDPLPYVWFAFHWLAMSHCCYNPIIYCYMNARFR---SGFVQL 397
            |..||.|.|...|||:.:.. |.:...|  |||||.|||..||||.|||::|..||   ...:.:
Mouse   358 FALCWFPLNCYVLLLSSKAI-HTNNALY--FAFHWFAMSSTCYNPFIYCWLNENFRVELKALLSM 419

  Fly   398 MHRMPGLRRWCCLRSVGDRMNATSGEM----TTKYHRHVGDALFRKPKICIRNGSSTSSQSNEHI 458
            ..|.|        :...||:.:.....    |.|.|..      |.|            ..|.|:
Mouse   420 CQRPP--------KPQEDRLPSPVPSFRVAWTEKSHGR------RAP------------LPNHHL 458

  Fly   459 HHLHQRSSKATSDIFASEPII 479
            .....:|.|  :|:.:.||::
Mouse   459 PSSQIQSGK--TDLSSVEPVV 477

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RYa-R	NP_001287552.1	7tm_4	113..>234	CDD:304433	45/177 (25%)
		7tm_1	122..383	CDD:278431	91/331 (27%)
Gpr83	XP_030099918.1	7tmA_GPR83	72..413	CDD:320511	100/358 (28%)
		TM helix 1	74..98	CDD:320511	7/23 (30%)
		TM helix 2	107..129	CDD:320511	7/21 (33%)
		TM helix 3	145..167	CDD:320511	10/21 (48%)
		TM helix 4	245..261	CDD:320511	6/29 (21%)
		TM helix 5	294..317	CDD:320511	6/22 (27%)
		TM helix 6	345..370	CDD:320511	10/24 (42%)
		TM helix 7	381..406	CDD:320511	16/26 (62%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910