Protein Alignment RYa-R and NPFFR2

DIOPT Version :9

• Sequence 1: NP_001287552.1
• Gene: RYa-R / 43253
• FlyBaseID: FBgn0004842
• Length: 518
• Species: Drosophila melanogaster
• Sequence 2: NP_001138228.1
• Gene: NPFFR2 / 10886
• HGNCID: 4525
• Length: 423
• Species: Homo sapiens
• Alignment Length: 365
• Identity: 117/365 - (32%)
• Similarity: 180/365 - (49%)
• Gaps: 47/365 - (12%)

  Fly   106 IIVYMLYIPIFIFALIGNGTVCYIVYSTPRMRTVTNYFIASLAIGDILMSFFCVPSSFISLFILN 170
            ||.|.|   ||...::||..||:||.....|.||||.||.:|||.|:|:..||:|.:.:...|..
Human    52 IISYFL---IFFLCMMGNTVVCFIVMRNKHMHTVTNLFILNLAISDLLVGIFCMPITLLDNIIAG 113

  Fly   171 YWPFGLALCHFVNYSQAVSVLVSAYTLVAISIDRYIAIMWPLKPRITKRYATFIIAGVWFIALAT 235
             ||||..:|......|.:||..|.:|||||::||:..:::|.||::|.:.|..||..:|.:|:..
Human   114 -WPFGNTMCKISGLVQGISVAASVFTLVAIAVDRFQCVVYPFKPKLTIKTAFVIIMIIWVLAITI 177

  Fly   236 ALPIPIVSGLDIPMSPWHTKCEKYI---------------CREMWPSRTQEYYYTLSLFALQFVV 285
            ..|..::         .|.:.|||.               |||.||::.....||..|||..::.
Human   178 MSPSAVM---------LHVQEEKYYRVRLNSQNKTSPVYWCREDWPNQEMRKIYTTVLFANIYLA 233

  Fly   286 PLGVLIFTYARITIRVWAKRPPGEAETNRDQ--RMARSKRKMVKMMLTVVIVFTCCWLPFNILQL 348
            ||.:::..|.||.|.::....|.....|::|  .::|.|:|::||:|.|.::|...|||...|.:
Human   234 PLSLIVIMYGRIGISLFRAAVPHTGRKNQEQWHVVSRKKQKIIKMLLIVALLFILSWLPLWTLMM 298

  Fly   349 LLNDEEFAHWDPLP------YVWFAFHWLAMSHCCYNPIIYCYMNARFRSGF-----VQLMHRMP 402
            |   .::|...|..      |::...||||..:...|||||.:.|..||.||     :||..:..
Human   299 L---SDYADLSPNELQIINIYIYPFAHWLAFGNSSVNPIIYGFFNENFRRGFQEAFQLQLCQKRA 360

  Fly   403 GLRRWCCLRSVGDRMNATSGEM---TTKYHRHVGDALFRK 439
            .......|::....:..||.::   :|..:.|....|:||
Human   361 KPMEAYALKAKSHVLINTSNQLVQESTFQNPHGETLLYRK 400

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RYa-R	NP_001287552.1	7tm_4	113..>234	CDD:304433	49/120 (41%)
		7tm_1	122..383	CDD:278431	94/283 (33%)
NPFFR2	NP_001138228.1	7tm_4	56..>178	CDD:304433	50/125 (40%)
		7tm_1	65..336	CDD:278431	94/283 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3897
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.940