Protein Alignment RYa-R and qrfpra

DIOPT Version :10

• Sequence 1: NP_001287552.1
• Gene: RYa-R / 43253
• FlyBaseID: FBgn0004842
• Length: 518
• Species: Drosophila melanogaster
• Sequence 2: XP_021336543.1
• Gene: qrfpra / 100149491
• ZFINID: ZDB-GENE-090313-105
• Length: 422
• Species: Danio rerio
• Alignment Length: 432
• Identity: 116/432 - (26%)
• Similarity: 198/432 - (45%)
• Gaps: 75/432 - (17%)

  Fly    91 YDLLSEDMWSSAYFKIIVY-------------MLYIPIFIFALIGNGTVCYIVYSTPRMRTVTNY 142
            |:|..::...:...:.:||             ::|..||:.||:||..|.|||.....::|.||.
Zfish    18 YNLTRQEFIETYQIEPLVYIPELPAGAKTTFVIVYTVIFLLALVGNSVVVYIVLRKRGIQTATNI 82

  Fly   143 FIASLAIGDILMSFFCVPSSFISLFILNYWPFGLALCHFVNYSQAVSVLVSAYTLVAISIDRYIA 207
            ||.|||:.|:|:||||:|.:.:. .|.:.|..|:.:|..|.:.|..:|:....|:..|:::||..
Zfish    83 FICSLAVSDLLISFFCIPFTLLQ-NISSEWFGGVLVCKTVPFVQTTAVVTGILTMTCIAVERYQG 146

  Fly   208 IMWPL--KPRITKRYATFIIAGVWFIALATALPIPIVSGLDIP---MSPWHTKCEKYICREMWPS 267
            |:.||  |.:.|.:.|..::..||..|:....|:..|..|::.   :...|..|    |:|.|.|
Zfish   147 IVHPLKIKRQCTPQRAYRMLGVVWIAAMMVGSPMLFVQQLEVKYDFLYDNHHVC----CQERWRS 207

  Fly   268 RTQEYYYTLSLFALQFVVPLGVLIFTYARITIRVWAKRPPGE-----AETNRD-QRMARSKRKMV 326
            ......|...:....|::||..::..|.||.|.:|.::..|:     |...|: .::||.||:.:
Zfish   208 SAHRKRYATFILVFLFLLPLAAMLILYTRIGIELWIRKQVGDSSVLNAMNQREVSKIARKKRRAI 272

  Fly   327 KMMLTVVIVFTCCWLPFNILQLLLNDEEFAH----WDPLP--YVWFAFHWLAMSHCCYNPIIYCY 385
            |||:|:|::||.||.||:.:.:|.   |:::    :|.:.  .:......:..|:...|||||.:
Zfish   273 KMMVTIVVLFTVCWAPFHTVHILF---EYSYLNKKYDDVTVNMIIAVAQAIGFSNSFNNPIIYAF 334

  Fly   386 MNARFRSGFVQLMHRMPGLRRWCCLRSVGDRMNATSGEMTTKYHRHVGDALFRKPKICIRNGSST 450
            ||..|:...:..:.        .|:|....|::.          :.....||.|          :
Zfish   335 MNENFQKNCMSTLS--------VCIRRSSHRVDV----------KDKSKVLFCK----------S 371

  Fly   451 SSQSNE-----HIHHLHQ----RSSKATSDIFASEPIIVRRD 483
            :.|..|     .||.:.|    ||:..||..|..|.:.|..:
Zfish   372 ARQDEEISVMPRIHIIDQVQYARSNMRTSMSFLEERMSVENN 413

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RYa-R	NP_001287552.1	7tmA_PR4-like	106..394	CDD:320514	96/317 (30%)
		TM helix 1	107..133	CDD:320514	13/38 (34%)
		TM helix 2	140..165	CDD:320514	14/24 (58%)
		TM helix 3	179..209	CDD:320514	8/29 (28%)
		TM helix 4	220..241	CDD:320514	5/20 (25%)
		TM helix 5	271..300	CDD:320514	7/28 (25%)
		TM helix 6	320..350	CDD:320514	14/29 (48%)
		TM helix 7	362..387	CDD:320514	6/26 (23%)
qrfpra	XP_021336543.1	7tmA_QRFPR	46..343	CDD:320333	94/304 (31%)
		TM helix 1	47..73	CDD:320333	11/25 (44%)
		TM helix 2	80..106	CDD:320333	14/26 (54%)
		TM helix 3	118..148	CDD:320333	8/29 (28%)
		TM helix 4	161..182	CDD:320333	5/20 (25%)
		TM helix 5	211..236	CDD:320333	5/24 (21%)
		TM helix 6	266..296	CDD:320333	14/29 (48%)
		TM helix 7	311..336	CDD:320333	6/24 (25%)