Protein Alignment RYa-R and tacr1

DIOPT Version :10

• Sequence 1: NP_001287552.1
• Gene: RYa-R / 43253
• FlyBaseID: FBgn0004842
• Length: 518
• Species: Drosophila melanogaster
• Sequence 2: NP_001106489.1
• Gene: tacr1 / 100127678
• XenbaseID: XB-GENE-5835469
• Length: 407
• Species: Xenopus tropicalis
• Alignment Length: 381
• Identity: 130/381 - (34%)
• Similarity: 195/381 - (51%)
• Gaps: 38/381 - (9%)

  Fly    98 MWSSAYFKIIVYMLYIPIFIFALIGNGTVCYIVYSTPRMRTVTNYFIASLAIGDILMSFFCVPSS 162
            :||.|| .|||        |.:::||..|.:|:.:..|||||||||:.:||..:..||.|....:
 Frog    34 LWSIAY-SIIV--------IVSVVGNIIVMWIILAHKRMRTVTNYFLVNLAFAEASMSAFNTVIN 89

  Fly   163 FISLFILNYWPFGLALCHFVNYSQAVSVLVSAYTLVAISIDRYIAIMWPLKPRITKRYATFIIAG 227
            | :..|.|:|.:||..|.|.|:....:|..|.|::.||::|||:||:.|||||::......:||.
 Frog    90 F-TYAIHNHWYYGLIYCKFHNFFPISAVFSSIYSMTAIALDRYMAIIHPLKPRLSATATRIVIAV 153

  Fly   228 VWFIALATALPIPIVSGLDIPMSPWHTKCEKYICREMWP---SRTQEYYYTLSLFALQFVVPLGV 289
            :|..|.|.|.|    .|....:.|   ..::.:|...||   :|..|..|.:.||.|.:.:||.|
 Frog   154 IWGFAFALAFP----QGYFATVEP---TPDRVVCYMEWPESENRKFEKVYQVLLFGLIYFLPLLV 211

  Fly   290 LIFTYARITIRVWAKRPPGEAETNRDQRMARSKRKMVKMMLTVVIVFTCCWLPFNI---LQLLLN 351
            :..:|..|.:.:||...||:: ::|......:|||:||||:.||..|..||||::|   |||.|.
 Frog   212 IGCSYTFIGMTLWASEIPGDS-SDRYHEQVVAKRKVVKMMIVVVCTFAICWLPYHIYFLLQLFLP 275

  Fly   352 DEEFAHWDPLPYVWFAFHWLAMSHCCYNPIIYCYMNARFRSGFVQLMHRMPGLRRWCCLRSVGDR 416
            ||....:..|   :....||.||...|||||||.:|.|||.||..:.       |||.....|:.
 Frog   276 DESQKFYQQL---YLGIMWLGMSSTMYNPIIYCCLNDRFRIGFKHVF-------RWCPFIHAGEY 330

  Fly   417 MNATSGEMTTKYHRHVGDALFRKPKICIRNGSSTSSQSNEHIHHLHQRSSKATSDI 472
            ...   ||.:..:.....::::..:| ....||..|.::|......:.|.:.:.|:
 Frog   331 EGL---EMKSTRYLQTQSSMYKISRI-ETTVSSVLSANDEDAEETTKSSKRLSLDL 382

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RYa-R	NP_001287552.1	7tmA_PR4-like	106..394	CDD:320514	111/293 (38%)
		TM helix 1	107..133	CDD:320514	7/25 (28%)
		TM helix 2	140..165	CDD:320514	10/24 (42%)
		TM helix 3	179..209	CDD:320514	12/29 (41%)
		TM helix 4	220..241	CDD:320514	7/20 (35%)
		TM helix 5	271..300	CDD:320514	10/28 (36%)
		TM helix 6	320..350	CDD:320514	18/32 (56%)
		TM helix 7	362..387	CDD:320514	11/24 (46%)
tacr1	NP_001106489.1	7tmA_NK1R	33..315	CDD:320668	115/301 (38%)
		TM helix 1	34..60	CDD:320668	12/34 (35%)
		TM helix 2	67..93	CDD:320668	10/26 (38%)
		TM helix 3	105..135	CDD:320668	12/29 (41%)
		TM helix 4	146..167	CDD:320668	7/24 (29%)
		TM helix 5	193..222	CDD:320668	10/28 (36%)
		TM helix 6	241..271	CDD:320668	15/29 (52%)
		TM helix 7	283..308	CDD:320668	12/27 (44%)