DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6271 and Pnlip

DIOPT Version :9

Sequence 1:	NP_651526.1	Gene:	CG6271 / 43252	FlyBaseID:	FBgn0039476	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_081201.2	Gene:	Pnlip / 69060	MGIID:	97722	Length:	465	Species:	Mus musculus

Alignment Length:	320	Identity:	100/320 - (31%)
Similarity:	145/320 - (45%)	Gaps:	46/320 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 WMEAQEKLEGRGLTTVPVNFYLFTPKNPSSSKHIYATTKSISKSNFNPAHPTRFVIHGWTQSYLN 115
            |..||          :...|.|:|.:||.:.:.|.:...:|..|||.....||.:|||:......
Mouse    46 WSPAQ----------INTRFLLYTNENPDNYQLITSDASNIRNSNFRTNRKTRIIIHGFIDKGEE 100

  Fly   116 SMNSDIRKAFLSKGDYNVIVVDWARARSVDYATSVMAVAATGKKVAKMINFLKDNHGLNLNDVYV 180
            :..||:.|........|.|.|||.......|..:...|...|.:||.::|.|:.:.|.:||:|::
Mouse   101 NWLSDMCKNMFRVESVNCICVDWKGGSRTTYTQATQNVRVVGAEVALLVNVLQSDLGYSLNNVHL 165

  Fly   181 IGHSLGAHVAGYAGKNTDGQVHTIIGLDPALPLFSYNKPNKRLNSDDAWYVESIQTNGGTL---- 241
            ||||||:|:||.|||.|.|.:..|.|||||.|.|.......||:..||.:|::|.|:.|.:
Mouse   166 IGHSLGSHIAGEAGKRTFGAIGRITGLDPAEPYFQGTPEEVRLDPTDAQFVDAIHTDAGPIIPNL 230

  Fly   242 --GFLKPIGKGAFYPNGGKTQPGCP-------LDVTG---------ACSHGRSTTYYAEA-VSED 287
              |..:.:|...|:||||...|||.       :|:.|         ||:|.||..:|.:: |:..
Mouse   231 GFGMSQTVGHLDFFPNGGIEMPGCQKNILSQIVDIDGIWEGTRNFAACNHLRSYKFYTDSIVNPT 295

  Fly   288 NFGTMKCGDYEEAVAKE---CGS-------TYSSVRMGADTNAYMVEGDFYVPVNSKAPF 337
            .|....|..|....|.:   |||       .|:....|..:..|..   ||:....|:.|
Mouse   296 GFAGFSCSSYSLFTANKCFPCGSGGCPQMGHYADRYPGKTSRLYQT---FYLNTGDKSNF 352

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6271	NP_651526.1	Lipase	57..337	CDD:278576	96/312 (31%)
CG6271	NP_651526.1	Pancreat_lipase_like	68..333	CDD:238363	95/297 (32%)
Pnlip	NP_081201.2	Lipase	18..352	CDD:278576	99/318 (31%)
		Pancreat_lipase_like	51..348	CDD:238363	95/299 (32%)
		PLAT_PL	355..465	CDD:238857
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167835381
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28N19
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.840