Sequence 1: | NP_651526.1 | Gene: | CG6271 / 43252 | FlyBaseID: | FBgn0039476 | Length: | 341 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_000228.1 | Gene: | LPL / 4023 | HGNCID: | 6677 | Length: | 475 | Species: | Homo sapiens |
Alignment Length: | 329 | Identity: | 95/329 - (28%) |
---|---|---|---|
Similarity: | 155/329 - (47%) | Gaps: | 46/329 - (13%) |
- Green bases have known domain annotations that are detailed below.
Fly 51 WMEAQEKLEG--------RGLTTVPVNFYLFTPKNPSSSK-H-IYATTKSISKSNFNPAHPTRFV 105
Fly 106 IHGWT-----QSYLNSMNSDIRKAFLSKGDYNVIVVDWARARSVDYATSVMAVAATGKKVAKMIN 165
Fly 166 FLKDNHGLNLNDVYVIGHSLGAHVAGYAGKNTDGQVHTIIGLDPALPLFSYNKPNKRLNSDDAWY 230
Fly 231 VESIQT-----NGGTLGFLKPIGKGAFYPNGGKTQPGC---------------PLDVTGACSHGR 275
Fly 276 STTYYAEA-VSEDN-FGTMKCGD---YEEAVAKECGSTYSSVRMGADTNAYMVE--GDFYVPVNS 333
Fly 334 KAPF 337 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
CG6271 | NP_651526.1 | Lipase | 57..337 | CDD:278576 | 93/321 (29%) |
Pancreat_lipase_like | 68..333 | CDD:238363 | 90/298 (30%) | ||
LPL | NP_000228.1 | Interaction with GPIHBP1. /evidence=ECO:0000269|PubMed:30559189 | 32..53 | 5/20 (25%) | |
Lipase | 33..473 | CDD:332983 | 92/310 (30%) | ||
Essential for determining substrate specificity. /evidence=ECO:0000269|PubMed:7592706 | 243..266 | 2/22 (9%) | |||
Important for interaction with lipoprotein particles. /evidence=ECO:0000269|PubMed:27929370 | 417..421 | ||||
Important for heparin binding. /evidence=ECO:0000269|PubMed:11342582 | 430..434 | ||||
Interaction with GPIHBP1. /evidence=ECO:0000269|PubMed:26725083, ECO:0000269|PubMed:30559189 | 443..467 | ||||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 1 | 0.930 | - | - | C165145306 | |
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 0 | 0.000 | Not matched by this tool. | |||
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 1 | 0.950 | - | 0 | Normalized mean entropy | S7604 |
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 1 | 1.100 | - | - | O | PTHR11610 |
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
4 | 3.890 |