DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6271 and lipca

DIOPT Version :9

Sequence 1:	NP_651526.1	Gene:	CG6271 / 43252	FlyBaseID:	FBgn0039476	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_957316.1	Gene:	lipca / 393997	ZFINID:	ZDB-GENE-040426-1361	Length:	514	Species:	Danio rerio

Alignment Length:	276	Identity:	74/276 - (26%)
Similarity:	128/276 - (46%)	Gaps:	46/276 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    90 SISKSNFNPAHPTRFVIHGWT-----QSYLNSMNSDIRKAFLSKGDYNVIVVDWARARSVDYATS 149
            ::....||.:.|...:||||:     :.:::.:.|.::.   |:|:.||::.||.......|..:
Zfish    68 TLDACGFNSSLPLAIIIHGWSVDGMMEKWISRLASALKS---SEGNINVLIADWLTLAHQHYPIA 129

  Fly   150 VMAVAATGKKVAKMINFLKDNHGLNLNDVYVIGHSLGAHVAGYAGKNTDGQVHT---IIGLDPAL 211
            .......|:.:|.::::|:|.....|..|::||:|||||::|:||.|......|   |.|||||.
Zfish   130 AQNTRIVGQDIAHLLSWLEDFKQFPLGKVHLIGYSLGAHISGFAGSNLAMSGRTLGRITGLDPAG 194

  Fly   212 PLFSYNKPNKRLNSDDAWYVESIQT-----NGGTLGFLKPIGKGAFYPNGGKTQPGCPL------ 265
            |:|.......||:.:||.:|::|.|     .|.::|..:|:....||||||..||||.|
Zfish   195 PMFEGMSHTDRLSPEDAKFVDAIHTFTLQRMGLSVGIKQPVAHFDFYPNGGSFQPGCQLHMQNIY 259

  Fly   266 -----------DVTGACSHGRSTTYYAEAV--SEDNFGTMKCGD---YEEAVAKEC--------G 306
                       :.|..|:|.|:...:.:::  .:......||.|   :::....:|        |
Zfish   260 AHLAQHGIMGFEQTVKCAHERAVHLFIDSLLNKDKQIMAYKCSDNTAFDKGNCLDCRKNRCNTLG 324

  Fly   307 STYSSVRMGADTNAYM 322
            .....||.|.....::
Zfish   325 YDIKKVRTGKSKRLFL 340

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6271	NP_651526.1	Lipase	57..337	CDD:278576	74/276 (27%)
CG6271	NP_651526.1	Pancreat_lipase_like	68..333	CDD:238363	74/276 (27%)
lipca	NP_957316.1	lipo_lipase	44..488	CDD:132274	74/276 (27%)
		Pancreat_lipase_like	54..344	CDD:238363	74/276 (27%)
		PLAT_LPL	351..485	CDD:238856
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170578568
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28N19
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.840