DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6271 and lipg

DIOPT Version :9

Sequence 1:	NP_651526.1	Gene:	CG6271 / 43252	FlyBaseID:	FBgn0039476	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_956422.1	Gene:	lipg / 393096	ZFINID:	ZDB-GENE-040426-699	Length:	500	Species:	Danio rerio

Alignment Length:	286	Identity:	86/286 - (30%)
Similarity:	144/286 - (50%)	Gaps:	48/286 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    89 KSISKSNFNPAHPTRFVIHGWT-----QSYLNSMNSDIRKAFLSKGDYNVIVVDWARARSVDYAT 148
            :||....||....|..:|||||     :|:::.:.:.:::   .:.:.||:||||....:..|..
Zfish    76 ESIVACGFNATLRTILIIHGWTMSGMFESWMHKLVAAVQR---RESEANVVVVDWLGLANQLYPD 137

  Fly   149 SVMAVAATGKKVAKMINFLKDNHGLNLNDVYVIGHSLGAHVAGYAGKNTDGQVHTIIGLDPALPL 213
            :|......|:.:|.::::|::...|.|.:|::||:|||||||||||...:|.:..|.|||||.|:
Zfish   138 AVNHTRRVGQSIATLLDWLQEEEQLQLENVHIIGYSLGAHVAGYAGTFVNGIIGRITGLDPAGPM 202

  Fly   214 F----SYNKPNKRLNSDDAWYVESIQTN-----GGTLGFLKPIGKGAFYPNGGKTQPGCPLD--- 266
            |    ||||    |:.|||.:|:.:.|.     |.::|..:|||....|||||..||||...
Zfish   203 FEGADSYNK----LSPDDADFVDVLHTYTRGALGVSIGIQEPIGHIDIYPNGGDVQPGCTFGEFL 263

  Fly   267 --VTG------ACSHGRSTTYYAEA-VSEDNFG-TMKC---GDYEEAVAKECGST------YSSV 312
              .:|      .|.|.|:...:.:: :::|:.. ..:|   ..:::.:...|...      |::.
Zfish   264 SAASGNFMEAMKCEHERAVHLFVDSLMNKDHVSYAFQCTGPDRFKKGICLSCRKNRCNSIGYNAK 328

  Fly   313 RMGADTNAYMVEGDFYVPVNSKAPFG 338
            :|....|:.|     |:...:..|||
Zfish   329 KMRKRRNSKM-----YLKTRADTPFG 349

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6271	NP_651526.1	Lipase	57..337	CDD:278576	83/283 (29%)
CG6271	NP_651526.1	Pancreat_lipase_like	68..333	CDD:238363	83/279 (30%)
lipg	NP_956422.1	lipo_lipase	55..488	CDD:132274	86/286 (30%)
		Pancreat_lipase_like	65..344	CDD:238363	83/279 (30%)
		PLAT_LPL	351..486	CDD:238856
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170578527
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.940