DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6271 and Lipc

DIOPT Version :9

Sequence 1:	NP_651526.1	Gene:	CG6271 / 43252	FlyBaseID:	FBgn0039476	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	XP_006243421.1	Gene:	Lipc / 24538	RGDID:	3009	Length:	510	Species:	Rattus norvegicus

Alignment Length:	321	Identity:	87/321 - (27%)
Similarity:	140/321 - (43%)	Gaps:	85/321 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    60 GRGLTTVP------------------VNFYLF-----------TPKNPSSSKHIYATTKSISKSN 95
            |:|:.|.|                  :.|.||           .|::|          :::.:..
  Rat    23 GQGVGTEPFGRNLGATEERKPLQKPEIRFLLFKDESDRLGCQLRPQHP----------ETLQECG 77

  Fly    96 FNPAHPTRFVIHGWTQSYLNSMNSD-----------------IRKAFLSKGD--YNVIVVDWARA 141
            ||.:||...:||||:.|...::..|                 |..|..|:..  .||.:|||...
  Rat    78 FNSSHPLVMIIHGWSGSESATVGKDSDNDSQVDGLLETWIWKIVGALKSRQSQPVNVGLVDWISL 142

  Fly   142 RSVDYATSVMAVAATGKKVAKMINFLKDNHGLNLNDVYVIGHSLGAHVAGYAGKNTDG--QVHTI 204
            ....||.:|......|::||.::.:|:::...:.:.|::||:||||||:|:||.:..|  ::..|
  Rat   143 AYQHYAIAVRNTRVVGQEVAALLLWLEESMKFSRSKVHLIGYSLGAHVSGFAGSSMGGKRKIGRI 207

  Fly   205 IGLDPALPLFSYNKPNKRLNSDDAWYVESIQT-----NGGTLGFLKPIGKGAFYPNGGKTQPGC- 263
            .|||||.|:|....||:||:.|||.:|::|.|     .|.::|..:||....||||||..||||
  Rat   208 TGLDPAGPMFEGTSPNERLSPDDANFVDAIHTFTREHMGLSVGIKQPIAHYDFYPNGGSFQPGCH 272

  Fly   264 --------------PLDVTGACSHGRSTTYYAEAVSEDN-----FGTMKCGDYEEAVAKEC 305
                          .:..|..|:|.||...:.:::...|     |.......:.:.:...|
  Rat   273 FLELYKHIAEHGLNAITQTIKCAHERSVHLFIDSLQHSNLQNTGFQCSNMDSFSQGLCLNC 333

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6271	NP_651526.1	Lipase	57..337	CDD:278576	87/321 (27%)
CG6271	NP_651526.1	Pancreat_lipase_like	68..333	CDD:238363	83/295 (28%)
Lipc	XP_006243421.1	Lipase	18..366	CDD:278576	87/321 (27%)
		Pancreat_lipase_like	47..362	CDD:238363	83/297 (28%)
		PLAT_LPL	369..504	CDD:238856
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166338953
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.940