| Sequence 1: | NP_651526.1 | Gene: | CG6271 / 43252 | FlyBaseID: | FBgn0039476 | Length: | 341 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_032535.2 | Gene: | Lpl / 16956 | MGIID: | 96820 | Length: | 474 | Species: | Mus musculus |
| Alignment Length: | 312 | Identity: | 95/312 - (30%) |
|---|---|---|---|
| Similarity: | 150/312 - (48%) | Gaps: | 38/312 - (12%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 60 GRGLTTVPVNFYLFTPKNPSSSK-H-IYATTKSISKSNFNPAHPTRFVIHGWT-----QSYLNSM 117
Fly 118 NSDIRKAFLSKGDYNVIVVDWARARSVDYATSVMAVAATGKKVAKMINFLKDNHGLNLNDVYVIG 182
Fly 183 HSLGAHVAGYAGKNTDGQVHTIIGLDPALPLFSYNKPNKRLNSDDAWYVESIQT-----NGGTLG 242
Fly 243 FLKPIGKGAFYPNGGKTQPGC---------------PLDVTGACSHGRSTTYYAEA-VSEDN-FG 290
Fly 291 TMKCGD---YEEAVAKECGSTYSSVRMGADTNAYMVE--GDFYVPVNSKAPF 337 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| CG6271 | NP_651526.1 | Lipase | 57..337 | CDD:278576 | 94/310 (30%) |
| Pancreat_lipase_like | 68..333 | CDD:238363 | 91/298 (31%) | ||
| Lpl | NP_032535.2 | Interaction with GPIHBP1. /evidence=ECO:0000250|UniProtKB:P06858 | 32..53 | 5/20 (25%) | |
| lipo_lipase | 33..472 | CDD:132274 | 93/310 (30%) | ||
| Pancreat_lipase_like | 37..334 | CDD:238363 | 91/300 (30%) | ||
| Essential for determining substrate specificity. /evidence=ECO:0000250|UniProtKB:P06858 | 243..266 | 2/22 (9%) | |||
| PLAT_LPL | 341..465 | CDD:238856 | |||
| Important for interaction with lipoprotein particles. /evidence=ECO:0000250|UniProtKB:P06858 | 417..421 | ||||
| Important for heparin binding. /evidence=ECO:0000250|UniProtKB:P06858 | 430..434 | ||||
| Interaction with GPIHBP1. /evidence=ECO:0000250|UniProtKB:P06858 | 443..467 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 1 | 0.950 | - | 0 | Normalized mean entropy | S7604 |
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 1 | 1.100 | - | - | O | PTHR11610 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 3 | 2.960 | |||||