DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6271 and Lipg

DIOPT Version :9

Sequence 1:	NP_651526.1	Gene:	CG6271 / 43252	FlyBaseID:	FBgn0039476	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_034850.3	Gene:	Lipg / 16891	MGIID:	1341803	Length:	500	Species:	Mus musculus

Alignment Length:	315	Identity:	100/315 - (31%)
Similarity:	154/315 - (48%)	Gaps:	50/315 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    64 TTVP------VNFYLFTPKNPSSS--KHIYATTKSISKSNFNPAHPTRFVIHGWT-----QSYLN 115
            |.||      |.|.:.|.|:|...  ......:|.:....||....|.|:|||||     :|:|:
Mouse    39 TGVPATARPSVAFNIRTSKDPEQEGCNLSLGDSKLLENCGFNMTAKTFFIIHGWTMSGMFESWLH 103

  Fly   116 SMNSDIRKAFLSKGDYNVIVVDWARARSVDYATSVMAVAATGKKVAKMINFLKDNHGLNLNDVYV 180
            .:.|.::   :.:.|.||:||||.......|..:|......|::||.|:::|::....:|.:|::
Mouse   104 KLVSALQ---MREKDANVVVVDWLPLAHQLYTDAVNNTRVVGQRVAGMLDWLQEKEEFSLGNVHL 165

  Fly   181 IGHSLGAHVAGYAGKNTDGQVHTIIGLDPALPLFSYNKPNKRLNSDDAWYVESIQTN----GGTL 241
            ||:|||||||||||....|.|..|.|||||.|:|.....|:||:.|||.:|:.:.|.    |.::
Mouse   166 IGYSLGAHVAGYAGNFVKGTVGRITGLDPAGPMFEGVDINRRLSPDDADFVDVLHTYTLSFGLSI 230

  Fly   242 GFLKPIGKGAFYPNGGKTQPGCPL-DVTGA-----------CSHGRSTTYYAEA-VSED--NFGT 291
            |...|:|....|||||..||||.. ||.|:           |.|.|:...:.:: |::|  :| .
Mouse   231 GIRMPVGHIDIYPNGGDFQPGCGFNDVIGSFAYGTISEMVKCEHERAVHLFVDSLVNQDKPSF-A 294

  Fly   292 MKCGD---YEEAVAKECGST------YSSVRMGADTNAYMVEGDFYVPVNSKAPF 337
            .:|.|   ::..:...|...      |::.:|....|:.|     |:...:..||
Mouse   295 FQCTDSSRFKRGICLSCRKNRCNNIGYNAKKMRKKRNSKM-----YLKTRAGMPF 344

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6271	NP_651526.1	Lipase	57..337	CDD:278576	98/313 (31%)
CG6271	NP_651526.1	Pancreat_lipase_like	68..333	CDD:238363	95/299 (32%)
Lipg	NP_034850.3	Pancreat_lipase_like	49..340	CDD:238363	95/299 (32%)
		lipo_lipase	51..485	CDD:132274	96/303 (32%)
		Heparin-binding. /evidence=ECO:0000250	325..337		4/16 (25%)
		PLAT_LPL	347..483	CDD:238856
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167835326
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.940