DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6277 and Pnlip

DIOPT Version :9

Sequence 1:	NP_651525.1	Gene:	CG6277 / 43251	FlyBaseID:	FBgn0039475	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_081201.2	Gene:	Pnlip / 69060	MGIID:	97722	Length:	465	Species:	Mus musculus

Alignment Length:	320	Identity:	96/320 - (30%)
Similarity:	145/320 - (45%)	Gaps:	46/320 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 WMEAQELLESRGLTTVPVKFYLYTSSNPTKGKKITASTKSIDASSFNSAHPTRFVIHGWTQSYTA 115
            |..||          :..:|.|||:.||...:.||:...:|..|:|.:...||.:|||:......
Mouse    46 WSPAQ----------INTRFLLYTNENPDNYQLITSDASNIRNSNFRTNRKTRIIIHGFIDKGEE 100

  Fly   116 SMNKDIRSAWLSRGDYNVIVVDWARARSVDYATSVLAVAATGKKVAKMINFLKDNHGLNLNDLYV 180
            :...|:..........|.|.|||.......|..:...|...|.:||.::|.|:.:.|.:||::::
Mouse   101 NWLSDMCKNMFRVESVNCICVDWKGGSRTTYTQATQNVRVVGAEVALLVNVLQSDLGYSLNNVHL 165

  Fly   181 IGHSLGAHVAGYAGKNTDGQVHTIIGLDPALPLFSYNKPNKRLNSDDAWYVESIQTNGGTL---- 241
            ||||||:|:||.|||.|.|.:..|.|||||.|.|.......||:..||.:|::|.|:.|.:
Mouse   166 IGHSLGSHIAGEAGKRTFGAIGRITGLDPAEPYFQGTPEEVRLDPTDAQFVDAIHTDAGPIIPNL 230

  Fly   242 --GFLKPIGKGAFYPNGGKTQPGCG-------LDLTG---------ACSHGRSTTYYAEA-VSED 287
              |..:.:|...|:||||...|||.       :|:.|         ||:|.||..:|.:: |:..
Mouse   231 GFGMSQTVGHLDFFPNGGIEMPGCQKNILSQIVDIDGIWEGTRNFAACNHLRSYKFYTDSIVNPT 295

  Fly   288 NFGTMKCGDYEEAVSKE---CGS-------TYSSVRMGADTNAYMVEGDYYVPVNSKAPF 337
            .|....|..|....:.:   |||       .|:....|..:..|..   :|:....|:.|
Mouse   296 GFAGFSCSSYSLFTANKCFPCGSGGCPQMGHYADRYPGKTSRLYQT---FYLNTGDKSNF 352

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6277	NP_651525.1	Pancreat_lipase_like	68..333	CDD:238363	91/297 (31%)
Pnlip	NP_081201.2	Lipase	18..352	CDD:278576	95/318 (30%)
		Pancreat_lipase_like	51..348	CDD:238363	91/299 (30%)
		PLAT_PL	355..465	CDD:238857
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167835380
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28N19
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.840