DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6277 and lipca

DIOPT Version :9

Sequence 1:	NP_651525.1	Gene:	CG6277 / 43251	FlyBaseID:	FBgn0039475	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_957316.1	Gene:	lipca / 393997	ZFINID:	ZDB-GENE-040426-1361	Length:	514	Species:	Danio rerio

Alignment Length:	305	Identity:	85/305 - (27%)
Similarity:	136/305 - (44%)	Gaps:	62/305 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    70 FYLYTSSNPTKGKKITASTK-----SIDASSFNSAHPTRFVIHGWTQSYTASMNKDIRSAWLSR- 128
            |.:||....|:.   |.:.:     ::||..|||:.|...:||||  |....|.|     |:||
Zfish    46 FRVYTDGEYTED---TCALELFQPHTLDACGFNSSLPLAIIIHGW--SVDGMMEK-----WISRL 100

  Fly   129 --------GDYNVIVVDWARARSVDYATSVLAVAATGKKVAKMINFLKDNHGLNLNDLYVIGHSL 185
                    |:.||::.||.......|..:.......|:.:|.::::|:|.....|..:::||:||
Zfish   101 ASALKSSEGNINVLIADWLTLAHQHYPIAAQNTRIVGQDIAHLLSWLEDFKQFPLGKVHLIGYSL 165

  Fly   186 GAHVAGYAGKNTDGQVHT---IIGLDPALPLFSYNKPNKRLNSDDAWYVESIQT-----NGGTLG 242
            |||::|:||.|......|   |.|||||.|:|.......||:.:||.:|::|.|     .|.::|
Zfish   166 GAHISGFAGSNLAMSGRTLGRITGLDPAGPMFEGMSHTDRLSPEDAKFVDAIHTFTLQRMGLSVG 230

  Fly   243 FLKPIGKGAFYPNGGKTQPGC-----------------GLDLTGACSHGRSTTYYAEAV--SEDN 288
            ..:|:....||||||..||||                 |.:.|..|:|.|:...:.:::  .:..
Zfish   231 IKQPVAHFDFYPNGGSFQPGCQLHMQNIYAHLAQHGIMGFEQTVKCAHERAVHLFIDSLLNKDKQ 295

  Fly   289 FGTMKCGD---YEEAVSKEC--------GSTYSSVRMGADTNAYM 322
            ....||.|   :::....:|        |.....||.|.....::
Zfish   296 IMAYKCSDNTAFDKGNCLDCRKNRCNTLGYDIKKVRTGKSKRLFL 340

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6277	NP_651525.1	Pancreat_lipase_like	68..333	CDD:238363	85/305 (28%)
lipca	NP_957316.1	lipo_lipase	44..488	CDD:132274	85/305 (28%)
		Pancreat_lipase_like	54..344	CDD:238363	82/297 (28%)
		PLAT_LPL	351..485	CDD:238856
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170578566
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28N19
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.840