DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6277 and lpl

DIOPT Version :9

Sequence 1:	NP_651525.1	Gene:	CG6277 / 43251	FlyBaseID:	FBgn0039475	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_571202.1	Gene:	lpl / 30354	ZFINID:	ZDB-GENE-990415-139	Length:	511	Species:	Danio rerio

Alignment Length:	327	Identity:	98/327 - (29%)
Similarity:	143/327 - (43%)	Gaps:	49/327 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 DGTSEWVDM-DV---AEQWMEAQELLESRGLTTVPVKFYLYTSSNPTKG--KKITASTKSIDASS 95
            |.|:|.:.: |:   |.:||        ...|.:..||...|...|...  ..:....:||...:
Zfish    31 DPTAESITLSDIIGNATEWM--------MDFTDIESKFSFRTLEEPEDDLCYIVPGQPQSIKDCN 87

  Fly    96 FNSAHPTRFVIHGWTQS--YTASMNKDIRSAWLSRGDYNVIVVDWARARSVDYATSVLAVAATGK 158
            ||:...|..||||||.:  :.:.:.|.:.:.:......|||||||.......|.||.......||
Zfish    88 FNTETKTFIVIHGWTVTGMFESWVPKLVTALYEREPSANVIVVDWLSRAQQHYPTSASYTKLVGK 152

  Fly   159 KVAKMINFLKDNHGLNLNDLYVIGHSLGAHVAGYAGKNTDGQVHTIIGLDPALPLFSYNKPNKRL 223
            .|||.:|:|:.........|:::|:||||||||.||..|..:|:.|.|:|||.|.|.|......|
Zfish   153 DVAKFVNWLQAEIDYPWEKLHLLGYSLGAHVAGIAGLLTKHKVNRITGMDPAGPTFEYADSLSTL 217

  Fly   224 NSDDAWYVESIQTN-----GGTLGFLKPIGKGAFYPNGGKTQPGCGLD-------LTG------- 269
            :.|||.:|:.:.||     ..::|..:|:|....|||||..||||.|.       .||
Zfish   218 SPDDANFVDVLHTNTRGSPDRSIGIQRPVGHIDIYPNGGTFQPGCDLQNTMLMVATTGLRNMDQI 282

  Fly   270 -ACSHGRSTTYYAEAV-------------SEDNFGTMKCGDYEEAVSKECGSTYSSVRMGADTNA 320
             .|||.||...:.:::             |.|:|....|....:....:.|...:.:|....:..
Zfish   283 VKCSHERSIHLFIDSLVNQDHESMAFRCSSRDSFNKGMCLSCRKNRCNKVGYAVNKIRTRRSSKM 347

  Fly   321 YM 322
            ||
Zfish   348 YM 349

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6277	NP_651525.1	Pancreat_lipase_like	68..333	CDD:238363	90/292 (31%)
lpl	NP_571202.1	lipo_lipase	52..492	CDD:132274	91/298 (31%)
		Pancreat_lipase_like	56..353	CDD:238363	90/294 (31%)
		PLAT	360..484	CDD:294016
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170578586
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.940