DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6277 and Lipg

DIOPT Version :9

Sequence 1:	NP_651525.1	Gene:	CG6277 / 43251	FlyBaseID:	FBgn0039475	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_001012759.1	Gene:	Lipg / 291437	RGDID:	1310740	Length:	493	Species:	Rattus norvegicus

Alignment Length:	308	Identity:	100/308 - (32%)
Similarity:	158/308 - (51%)	Gaps:	39/308 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    63 LTTVP-VKFYLYTSSNPT-KGKKIT-ASTKSIDASSFNSAHPTRFVIHGWTQS--YTASMNKDIR 122
            :||.| |.|.:.||.:|. :|..:: ..:|.::...||....|.|:|||||.|  :.:.::|.:.
  Rat    45 ITTKPSVTFNIRTSKDPEHEGCNLSLGDSKLLENCGFNMTAKTFFIIHGWTMSGMFESWLHKLVS 109

  Fly   123 SAWLSRGDYNVIVVDWARARSVDYATSVLAVAATGKKVAKMINFLKDNHGLNLNDLYVIGHSLGA 187
            :......:.||:||||.......|..:|......|::||.|:|:|::....:|.|:::||:||||
  Rat   110 ALQTREKEANVVVVDWLPLAHQLYIDAVSNTRVVGRRVAGMLNWLQEKGEFSLGDVHLIGYSLGA 174

  Fly   188 HVAGYAGKNTDGQVHTIIGLDPALPLFSYNKPNKRLNSDDAWYVESIQTN----GGTLGFLKPIG 248
            |||||||....|.|..|.|||||.|:|.....|:||:.|||.:|:.:.|.    |.::|...|:|
  Rat   175 HVAGYAGNFVKGTVGRITGLDPAGPMFEGVDINRRLSPDDADFVDVLHTYTLSFGLSIGIRMPVG 239

  Fly   249 KGAFYPNGGKTQPGCGL-DLTGA-----------CSHGRSTTYYAEA-VSED--NFGTMKCGD-- 296
            ....|||||..|||||. |:.|:           |.|.|:...:.:: |::|  :| ..:|.|
  Rat   240 HIDIYPNGGDFQPGCGFNDVMGSFAYGTISEMVKCEHERAVHLFVDSLVNQDKPSF-AFQCTDPN 303

  Fly   297 -YEEAVSKECGST------YSSVRMGADTNAYMVEGDYYVPVNSKAPF 337
             ::..:...|...      |::.:|....|:.|     |:...:..||
  Rat   304 RFKRGICLSCRKNRCNNIGYNAKKMRKKRNSKM-----YLKTRAGMPF 346

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6277	NP_651525.1	Pancreat_lipase_like	68..333	CDD:238363	95/296 (32%)
Lipg	NP_001012759.1	Pancreat_lipase_like	51..342	CDD:238363	95/296 (32%)
		lipo_lipase	53..488	CDD:132274	96/300 (32%)
		Heparin-binding. /evidence=ECO:0000250	327..339		4/16 (25%)
		PLAT_LPL	349..485	CDD:238856
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166338927
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.940