DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6277 and Pnlip

DIOPT Version :9

Sequence 1:	NP_651525.1	Gene:	CG6277 / 43251	FlyBaseID:	FBgn0039475	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_037293.2	Gene:	Pnlip / 25702	RGDID:	3360	Length:	465	Species:	Rattus norvegicus

Alignment Length:	376	Identity:	109/376 - (28%)
Similarity:	161/376 - (42%)	Gaps:	68/376 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 LILAFFALAASAIPIKE---------SERVHGENGWYVPQEDGTSEWVDMDV-AEQWMEAQELLE 59
            |:|..||:...|:..||         |:    :..|     .||   :|..: |..|..||
  Rat     2 LMLWTFAVLLGAVAGKEVCFDKLGCFSD----DAPW-----SGT---IDRPLKALPWSPAQ---- 50

  Fly    60 SRGLTTVPVKFYLYTSSNPTKGKKITASTKSIDASSFNSAHPTRFVIHGWTQSYTASMNKDIRSA 124
                  :..:|.|||:.|....:|||:...||..|:|.:...||.:|||:......:...|:...
  Rat    51 ------INTRFLLYTNENQDNYQKITSDASSIRNSNFKTNRKTRIIIHGFIDKGEENWLSDMCKN 109

  Fly   125 WLSRGDYNVIVVDWARARSVDYATSVLAVAATGKKVAKMINFLKDNHGLNLNDLYVIGHSLGAHV 189
            .......|.|.|||.......|..:...|...|.:||.::|.||.:.|.:.:::::||||||:||
  Rat   110 MFKVESVNCICVDWKGGSRATYTQATQNVRVVGAEVALLVNVLKSDLGYSPDNVHLIGHSLGSHV 174

  Fly   190 AGYAGKNTDGQVHTIIGLDPALPLFSYNKPNKRLNSDDAWYVESIQTNGGTL------GFLKPIG 248
            ||.|||.|.|.:..|.|||.|.|.|.......||:..||.:|::|.|:...:      |..:.:|
  Rat   175 AGEAGKRTFGAIGRITGLDAAEPYFQGTPEEVRLDPTDAQFVDAIHTDAAPIIPNLGFGMSQTVG 239

  Fly   249 KGAFYPNGGKTQPGCG-------LDLTG---------ACSHGRSTTYYAEA-VSEDNFGTMKCGD 296
            ...|:||||...|||.       :|:.|         ||:|.||..||.:: |:...|....|..
  Rat   240 HLDFFPNGGMEMPGCQKNILSQIVDIDGIWEGTRDFAACNHLRSYKYYTDSIVNPTGFSGFSCSS 304

  Fly   297 YEEAVSKE---CGST-------YSSVRMGADTNAYMVEGDYYVPVNSKAPF 337
            |....:.:   |||.       |:....|.....|.   .:|:....|:.|
  Rat   305 YNVFSANKCFPCGSEGCPQMGHYADKYPGKTKELYQ---KFYLNTGDKSNF 352

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6277	NP_651525.1	Pancreat_lipase_like	68..333	CDD:238363	91/297 (31%)
Pnlip	NP_037293.2	Lipase	17..352	CDD:395099	103/359 (29%)
Pnlip	NP_037293.2	PLAT_PL	355..465	CDD:238857
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166338992
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28N19
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.840