DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6277 and Lipg

DIOPT Version :9

Sequence 1:	NP_651525.1	Gene:	CG6277 / 43251	FlyBaseID:	FBgn0039475	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_034850.3	Gene:	Lipg / 16891	MGIID:	1341803	Length:	500	Species:	Mus musculus

Alignment Length:	312	Identity:	99/312 - (31%)
Similarity:	158/312 - (50%)	Gaps:	44/312 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    64 TTVP------VKFYLYTSSNP-TKGKKIT-ASTKSIDASSFNSAHPTRFVIHGWTQS--YTASMN 118
            |.||      |.|.:.||.:| .:|..:: ..:|.::...||....|.|:|||||.|  :.:.::
Mouse    39 TGVPATARPSVAFNIRTSKDPEQEGCNLSLGDSKLLENCGFNMTAKTFFIIHGWTMSGMFESWLH 103

  Fly   119 KDIRSAWLSRGDYNVIVVDWARARSVDYATSVLAVAATGKKVAKMINFLKDNHGLNLNDLYVIGH 183
            |.:.:..:...|.||:||||.......|..:|......|::||.|:::|::....:|.::::||:
Mouse   104 KLVSALQMREKDANVVVVDWLPLAHQLYTDAVNNTRVVGQRVAGMLDWLQEKEEFSLGNVHLIGY 168

  Fly   184 SLGAHVAGYAGKNTDGQVHTIIGLDPALPLFSYNKPNKRLNSDDAWYVESIQTN----GGTLGFL 244
            |||||||||||....|.|..|.|||||.|:|.....|:||:.|||.:|:.:.|.    |.::|..
Mouse   169 SLGAHVAGYAGNFVKGTVGRITGLDPAGPMFEGVDINRRLSPDDADFVDVLHTYTLSFGLSIGIR 233

  Fly   245 KPIGKGAFYPNGGKTQPGCGL-DLTGA-----------CSHGRSTTYYAEA-VSED--NFGTMKC 294
            .|:|....|||||..|||||. |:.|:           |.|.|:...:.:: |::|  :| ..:|
Mouse   234 MPVGHIDIYPNGGDFQPGCGFNDVIGSFAYGTISEMVKCEHERAVHLFVDSLVNQDKPSF-AFQC 297

  Fly   295 GD---YEEAVSKECGST------YSSVRMGADTNAYMVEGDYYVPVNSKAPF 337
            .|   ::..:...|...      |::.:|....|:.|     |:...:..||
Mouse   298 TDSSRFKRGICLSCRKNRCNNIGYNAKKMRKKRNSKM-----YLKTRAGMPF 344

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6277	NP_651525.1	Pancreat_lipase_like	68..333	CDD:238363	94/296 (32%)
Lipg	NP_034850.3	Pancreat_lipase_like	49..340	CDD:238363	94/296 (32%)
		lipo_lipase	51..485	CDD:132274	95/300 (32%)
		Heparin-binding. /evidence=ECO:0000250	325..337		4/16 (25%)
		PLAT_LPL	347..483	CDD:238856
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167835325
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S7752
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.890