DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6277 and Lipc

DIOPT Version :9

Sequence 1:	NP_651525.1	Gene:	CG6277 / 43251	FlyBaseID:	FBgn0039475	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	XP_006510879.1	Gene:	Lipc / 15450	MGIID:	96216	Length:	526	Species:	Mus musculus

Alignment Length:	333	Identity:	94/333 - (28%)
Similarity:	156/333 - (46%)	Gaps:	62/333 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    60 SRGLTTVPVKFYLYTSSNPTKGKKITAS-TKSIDASSFNSAHPTRFVIHGWTQSYTASMNKD--- 120
            |:.|.....:|.|:...|...|.::... .:::....|||:.|...:||||:.|.:|::.||
Mouse    41 SKPLKKPETRFLLFQDENDRLGCRLRPQHPETLQECGFNSSQPLIMIIHGWSGSESATVGKDSDS 105

  Fly   121 --------------IRSAWLSRGD--YNVIVVDWARARSVDYATSVLAVAATGKKVAKMINFLKD 169
                          |.||..||..  .||.:|||.......|..:|......|:.||.::.:|::
Mouse   106 DYQVDGLLENWIWKIVSALKSRQSQPVNVGLVDWISLAYQHYTIAVQNTRIVGQDVAALLLWLEE 170

  Fly   170 NHGLNLNDLYVIGHSLGAHVAGYAGKNTDG--QVHTIIGLDPALPLFSYNKPNKRLNSDDAWYVE 232
            :...:.:.:::||:||||||:|:||.:.||  ::..|.|||||.|:|....||:||:.|||.:|:
Mouse   171 SAKFSRSKVHLIGYSLGAHVSGFAGSSMDGKNKIGRITGLDPAGPMFEGTSPNERLSPDDANFVD 235

  Fly   233 SIQT-----NGGTLGFLKPIGKGAFYPNGGKTQPGC------------GLDL---TGACSHGRST 277
            :|.|     .|.::|..:||....||||||..||||            ||:.   |..|:|.||.
Mouse   236 AIHTFTREHMGLSVGIKQPIAHYDFYPNGGSFQPGCHFLELYKHIAEHGLNAITQTIKCAHERSV 300

  Fly   278 TYYAEAVSEDNFGTM--KC---GDYEEAVSKEC--------GSTYSSVRMGADTNAYMVEGDYYV 329
            ..:.:::...:..::  :|   |.:.:.:...|        |......|.|.....:::
Mouse   301 HLFIDSLQHSDLQSIGFQCSDMGSFSQGLCLSCKKGRCNTLGYDIRKDRSGKSKRLFLI------ 359

  Fly   330 PVNSKAPF 337
             ..:::||
Mouse   360 -TRAQSPF 366

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6277	NP_651525.1	Pancreat_lipase_like	68..333	CDD:238363	90/319 (28%)
Lipc	XP_006510879.1	Lipase	18..366	CDD:333880	92/331 (28%)
Lipc	XP_006510879.1	PLAT_LPL	369..504	CDD:238856
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167835350
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28N19
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.840