DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6283 and PNLIPRP1

DIOPT Version :9

Sequence 1:	NP_651524.1	Gene:	CG6283 / 43250	FlyBaseID:	FBgn0039474	Length:	339	Species:	Drosophila melanogaster
Sequence 2:	NP_001290064.1	Gene:	PNLIPRP1 / 5407	HGNCID:	9156	Length:	467	Species:	Homo sapiens

Alignment Length:	262	Identity:	84/262 - (32%)
Similarity:	119/262 - (45%)	Gaps:	28/262 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    67 FYVYTKSNPTDGKEIKAKSGS-VEDSHFNKDHGTRFVIHGWTQRYSDDMNTRITKAWLSKGDYNV 130
            |.:||..||.:.:.:.....| :|.|:|..|..|||:|||:..:..:...|.:.|......:.|.
Human    56 FLLYTNENPNNFQILLLSDPSTIEASNFQMDRKTRFIIHGFIDKGDESWVTDMCKKLFEVEEVNC 120

  Fly   131 IVVDWARARSVDYASSVLAVPGAGGKVGEMIKYLHDHHGLDYDSLEVIGHSLGAHVAGYAG-KTV 194
            |.|||.:.....|..:...|...|.:|.:|:..|...:......:.:|||||||||||.|| ||.
Human   121 ICVDWKKGSQATYTQAANNVRVVGAQVAQMLDILLTEYSYPPSKVHLIGHSLGAHVAGEAGSKTP 185

  Fly   195 GDKRVHTIVGLDPALPLFSYDKPAKRLSTDDAHYVESIQTNGGKL------GFLKPIGKGAFYPN 253
            |..|   |.||||....|.......||...||.:|:.|.|:...|      |..:.:|...|:||
Human   186 GLSR---ITGLDPVEASFESTPEEVRLDPSDADFVDVIHTDAAPLIPFLGFGTNQQMGHLDFFPN 247

  Fly   254 GGKSQPGCGLDATG----------------SCSHARSVLYYAEAV-TEDNFGSIKCHDYEDAVAK 301
            ||:|.|||..:|..                :|:|.||..||.|:: ..|.|.:..|..|:...:.
Human   248 GGESMPGCKKNALSQIVDLDGIWAGTRDFVACNHLRSYKYYLESILNPDGFAAYPCTSYKSFESD 312

  Fly   302 NC 303
            .|
Human   313 KC 314

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6283	NP_651524.1	Pancreat_lipase_like	65..331	CDD:238363	84/262 (32%)
PNLIPRP1	NP_001290064.1	Lipase	18..353	CDD:278576	84/262 (32%)
		Pancreat_lipase_like	52..349	CDD:238363	84/262 (32%)
		PLAT_PL	356..467	CDD:238857
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145287
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28N19
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.840