DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6283 and Lipg

DIOPT Version :9

Sequence 1:	NP_651524.1	Gene:	CG6283 / 43250	FlyBaseID:	FBgn0039474	Length:	339	Species:	Drosophila melanogaster
Sequence 2:	NP_001012759.1	Gene:	Lipg / 291437	RGDID:	1310740	Length:	493	Species:	Rattus norvegicus

Alignment Length:	318	Identity:	100/318 - (31%)
Similarity:	146/318 - (45%)	Gaps:	67/318 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    64 AVNFYVYTKSNPT-DGKEIK-AKSGSVEDSHFNKDHGTRFVIHGWTQRYSDDMNTRITKAWLSK- 125
            :|.|.:.|..:|. :|..:. ..|..:|:..||....|.|:|||||.       :.:.::||.|
  Rat    50 SVTFNIRTSKDPEHEGCNLSLGDSKLLENCGFNMTAKTFFIIHGWTM-------SGMFESWLHKL 107

  Fly   126 --------GDYNVIVVDW---ARARSVDYASSVLAVPGAGGKVGEMIKYLHDHHGLDYDSLEVIG 179
                    .:.||:||||   |....:|..|:...|   |.:|..|:.:|.:........:.:||
  Rat   108 VSALQTREKEANVVVVDWLPLAHQLYIDAVSNTRVV---GRRVAGMLNWLQEKGEFSLGDVHLIG 169

  Fly   180 HSLGAHVAGYAGK----TVGDKRVHTIVGLDPALPLFSYDKPAKRLSTDDAHYVESIQTN----G 236
            :|||||||||||.    |||     .|.|||||.|:|......:|||.|||.:|:.:.|.    |
  Rat   170 YSLGAHVAGYAGNFVKGTVG-----RITGLDPAGPMFEGVDINRRLSPDDADFVDVLHTYTLSFG 229

  Fly   237 GKLGFLKPIGKGAFYPNGGKSQPGCGL-DATGS-----------CSHARSV-LYYAEAVTED--N 286
            ..:|...|:|....|||||..|||||. |..||           |.|.|:| |:....|.:|  :
  Rat   230 LSIGIRMPVGHIDIYPNGGDFQPGCGFNDVMGSFAYGTISEMVKCEHERAVHLFVDSLVNQDKPS 294

  Fly   287 FGSIKCHD---YEDAVAKNCGST------YSSVRMGAITNAYMVEGDFYVPVNSEAPF 335
            | :.:|.|   ::..:..:|...      |::.:|....|:.|     |:...:..||
  Rat   295 F-AFQCTDPNRFKRGICLSCRKNRCNNIGYNAKKMRKKRNSKM-----YLKTRAGMPF 346

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6283	NP_651524.1	Pancreat_lipase_like	65..331	CDD:238363	98/311 (32%)
Lipg	NP_001012759.1	Pancreat_lipase_like	51..342	CDD:238363	98/311 (32%)
		lipo_lipase	53..488	CDD:132274	99/315 (31%)
		Heparin-binding. /evidence=ECO:0000250	327..339		4/16 (25%)
		PLAT_LPL	349..485	CDD:238856
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166338929
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.940