DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6283 and Pnliprp2

DIOPT Version :9

Sequence 1:	NP_651524.1	Gene:	CG6283 / 43250	FlyBaseID:	FBgn0039474	Length:	339	Species:	Drosophila melanogaster
Sequence 2:	NP_035258.2	Gene:	Pnliprp2 / 18947	MGIID:	1336202	Length:	482	Species:	Mus musculus

Alignment Length:	336	Identity:	95/336 - (28%)
Similarity:	142/336 - (42%)	Gaps:	55/336 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKVFFVLAALLAAVSALPIEERVNGENGWF---------IPKLDGSFEWMDMQDAEDLLANGAQM 56
            |.:.::::.|||.|..   :|...|..|.|         |.:....|.|    ..||:
Mouse    15 MLLCWLVSLLLATVGG---KEVCYGHLGCFSNDKPWAGMIQRPSKIFPW----SPEDI------- 65

  Fly    57 EGRISTNAVNFYVYTKSNPTDGKEIKAKS-GSVEDSHFNKDHGTRFVIHGWTQRYSDDMNTRITK 120
                   ...|.:||..||.:.:.|.|.. .::..|:|..|..|||:|||:..:..:.....:.|
Mouse    66 -------DTRFLLYTNENPNNYQIISATDPATINASNFQLDRKTRFIIHGFIDKGEEGWLLDMCK 123

  Fly   121 AWLSKGDYNVIVVDWARARSVDYASSVLAVPGAGGKVGEMIKYLHDHHGLDYDSLEVIGHSLGAH 185
            ........|.|.|||.|....:|..:.......|.::..:::.|....|...:::.:||||||:|
Mouse   124 KMFQVEKVNCICVDWKRGSRTEYTQASYNTRVVGAEIAFLVQVLSTEMGYSPENVHLIGHSLGSH 188

  Fly   186 VAGYAGKTVGDKRVHTIVGLDPALPLFSYDKPAKRLSTDDAHYVESIQTNGGKL------GFLKP 244
            |||.||:.: :..|..|.|||||.|.|.......||...||.:|:.|.|:...:      |..:.
Mouse   189 VAGEAGRRL-EGHVGRITGLDPAEPCFQGLPEEVRLDPSDAMFVDVIHTDSAPIIPYLGFGMSQK 252

  Fly   245 IGKGAFYPNGGKSQPGCG-------LDATG---------SCSHARSVLYYAEAV-TEDNFGSIKC 292
            :|...|:|||||..|||.       :|..|         :|:|.||..|||.:: ..|.|....|
Mouse   253 VGHLDFFPNGGKEMPGCQKNILSTIVDINGIWEGTRNFAACNHLRSYKYYASSILNPDGFLGYPC 317

  Fly   293 HDYEDAVAKNC 303
            ..||.....:|
Mouse   318 SSYEKFQHNDC 328

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6283	NP_651524.1	Pancreat_lipase_like	65..331	CDD:238363	81/263 (31%)
Pnliprp2	NP_035258.2	Lipase	31..367	CDD:278576	90/317 (28%)
		Pancreat_lipase_like	65..363	CDD:238363	81/279 (29%)
		Required for galactolipase activity. /evidence=ECO:0000250\|UniProtKB:P54317	106..118		3/11 (27%)
		Required for galactolipase activity. /evidence=ECO:0000250\|UniProtKB:P54317	270..292		2/21 (10%)
		PLAT_PL	370..482	CDD:238857
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167835372
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28N19
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.840