DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6283 and Lipg

DIOPT Version :9

Sequence 1:	NP_651524.1	Gene:	CG6283 / 43250	FlyBaseID:	FBgn0039474	Length:	339	Species:	Drosophila melanogaster
Sequence 2:	NP_034850.3	Gene:	Lipg / 16891	MGIID:	1341803	Length:	500	Species:	Mus musculus

Alignment Length:	315	Identity:	99/315 - (31%)
Similarity:	144/315 - (45%)	Gaps:	61/315 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    64 AVNFYVYTKSNP-TDGKEIK-AKSGSVEDSHFNKDHGTRFVIHGWTQRYSDDMNTRITKAWLSK- 125
            :|.|.:.|..:| .:|..:. ..|..:|:..||....|.|:|||||.       :.:.::||.|
Mouse    48 SVAFNIRTSKDPEQEGCNLSLGDSKLLENCGFNMTAKTFFIIHGWTM-------SGMFESWLHKL 105

  Fly   126 --------GDYNVIVVDWARARSVDYASSVLAVPGAGGKVGEMIKYLHDHHGLDYDSLEVIGHSL 182
                    .|.||:||||.......|..:|......|.:|..|:.:|.:.......::.:||:||
Mouse   106 VSALQMREKDANVVVVDWLPLAHQLYTDAVNNTRVVGQRVAGMLDWLQEKEEFSLGNVHLIGYSL 170

  Fly   183 GAHVAGYAGK----TVGDKRVHTIVGLDPALPLFSYDKPAKRLSTDDAHYVESIQTN----GGKL 239
            |||||||||.    |||     .|.|||||.|:|......:|||.|||.:|:.:.|.    |..:
Mouse   171 GAHVAGYAGNFVKGTVG-----RITGLDPAGPMFEGVDINRRLSPDDADFVDVLHTYTLSFGLSI 230

  Fly   240 GFLKPIGKGAFYPNGGKSQPGCGL-DATGS-----------CSHARSV-LYYAEAVTED--NFGS 289
            |...|:|....|||||..|||||. |..||           |.|.|:| |:....|.:|  :| :
Mouse   231 GIRMPVGHIDIYPNGGDFQPGCGFNDVIGSFAYGTISEMVKCEHERAVHLFVDSLVNQDKPSF-A 294

  Fly   290 IKCHD---YEDAVAKNCGST------YSSVRMGAITNAYMVEGDFYVPVNSEAPF 335
            .:|.|   ::..:..:|...      |::.:|....|:.|     |:...:..||
Mouse   295 FQCTDSSRFKRGICLSCRKNRCNNIGYNAKKMRKKRNSKM-----YLKTRAGMPF 344

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6283	NP_651524.1	Pancreat_lipase_like	65..331	CDD:238363	97/308 (31%)
Lipg	NP_034850.3	Pancreat_lipase_like	49..340	CDD:238363	97/308 (31%)
		lipo_lipase	51..485	CDD:132274	98/312 (31%)
		Heparin-binding. /evidence=ECO:0000250	325..337		4/16 (25%)
		PLAT_LPL	347..483	CDD:238856
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167835327
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.940