DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17191 and Lipg

DIOPT Version :9

Sequence 1:	NP_651523.1	Gene:	CG17191 / 43249	FlyBaseID:	FBgn0039473	Length:	337	Species:	Drosophila melanogaster
Sequence 2:	NP_034850.3	Gene:	Lipg / 16891	MGIID:	1341803	Length:	500	Species:	Mus musculus

Alignment Length:	313	Identity:	96/313 - (30%)
Similarity:	150/313 - (47%)	Gaps:	49/313 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 TRSNDVSFYLYTKHNP-------TVGKEIRADASSIEDSHFDKNQGTRFVIHGW--NGRYTDGMN 113
            |....|:|.:.|..:|       ::|     |:..:|:..|:....|.|:||||  :|.:...::
Mouse    44 TARPSVAFNIRTSKDPEQEGCNLSLG-----DSKLLENCGFNMTAKTFFIIHGWTMSGMFESWLH 103

  Fly   114 VKITRAWLSKGDYNVIVVNWDRAQSVDYISSVRAVPGAGAKVGEMIEYLHEHHHLSMESLEVIGH 178
            ..::...:.:.|.||:||:|.......|..:|......|.:|..|:::|.|....|:.::.:||:
Mouse   104 KLVSALQMREKDANVVVVDWLPLAHQLYTDAVNNTRVVGQRVAGMLDWLQEKEEFSLGNVHLIGY 168

  Fly   179 SLGAHVAGYAGKQVGGKRVHTIVGLDPAMPLFAYDKPDKRLSTEDAFYVESIQTN----GGEKGF 239
            |||||||||||..|.| .|..|.|||||.|:|.....::|||.:||.:|:.:.|.    |...|.
Mouse   169 SLGAHVAGYAGNFVKG-TVGRITGLDPAGPMFEGVDINRRLSPDDADFVDVLHTYTLSFGLSIGI 232

  Fly   240 LKPIGKGTFYPNGGRNQPGCG-SDIGGT-----------CAHGRSVTYYVEA-VTED--NFGTIK 289
            ..|:|....|||||..||||| :|:.|:           |.|.|:|..:|:: |.:|  :| ..:
Mouse   233 RMPVGHIDIYPNGGDFQPGCGFNDVIGSFAYGTISEMVKCEHERAVHLFVDSLVNQDKPSF-AFQ 296

  Fly   290 CHDYQ--------AALANECGST-YSGVRMGAVTNAYMVDGDFYVPVNGQAPF 333
            |.|..        :...|.|.:. |:..:|....|:.|     |:......||
Mouse   297 CTDSSRFKRGICLSCRKNRCNNIGYNAKKMRKKRNSKM-----YLKTRAGMPF 344

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17191	NP_651523.1	Pancreat_lipase_like	62..328	CDD:238363	93/302 (31%)
Lipg	NP_034850.3	Pancreat_lipase_like	49..340	CDD:238363	93/302 (31%)
		lipo_lipase	51..485	CDD:132274	94/306 (31%)
		Heparin-binding. /evidence=ECO:0000250	325..337		4/16 (25%)
		PLAT_LPL	347..483	CDD:238856
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167835329
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.940