DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17192 and PNLIPRP1

DIOPT Version :9

Sequence 1:	NP_651522.1	Gene:	CG17192 / 43248	FlyBaseID:	FBgn0039472	Length:	337	Species:	Drosophila melanogaster
Sequence 2:	NP_001290064.1	Gene:	PNLIPRP1 / 5407	HGNCID:	9156	Length:	467	Species:	Homo sapiens

Alignment Length:	262	Identity:	89/262 - (33%)
Similarity:	124/262 - (47%)	Gaps:	28/262 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    65 FYLYTKQNPTEGQ-EITADASSIVASHFNKDHGTRFVIHGWKGKYTDSMNVDITKAWLSKGDFNV 128
            |.|||.:||...| .:.:|.|:|.||:|..|..|||:|||:..|..:|...|:.|......:.|.
Human    56 FLLYTNENPNNFQILLLSDPSTIEASNFQMDRKTRFIIHGFIDKGDESWVTDMCKKLFEVEEVNC 120

  Fly   129 IVVNWARSQSVDYAMSVRAVPGAGTKVGEMIQYMHENHDMSLETLEVIGHSLGAHVAGYAG-KQV 192
            |.|:|.:.....|..:...|...|.:|.:|:..:...:......:.:|||||||||||.|| |..
Human   121 ICVDWKKGSQATYTQAANNVRVVGAQVAQMLDILLTEYSYPPSKVHLIGHSLGAHVAGEAGSKTP 185

  Fly   193 GQKRVHTIVGLDPALPLFSYDNPDKRLSSEDAFYVESIQTNGGVK------GFVKPIGKAAFYVS 251
            |..|   |.||||....|.....:.||...||.:|:.|.|:....      |..:.:|...|:.:
Human   186 GLSR---ITGLDPVEASFESTPEEVRLDPSDADFVDVIHTDAAPLIPFLGFGTNQQMGHLDFFPN 247

  Fly   252 GGRKQPGCG-------VDL----AGT-----CSHARSVIYYAEAI-TENSFGAIQCQDYQAALDN 299
            ||...|||.       |||    |||     |:|.||..||.|:| ..:.|.|..|..|::...:
Human   248 GGESMPGCKKNALSQIVDLDGIWAGTRDFVACNHLRSYKYYLESILNPDGFAAYPCTSYKSFESD 312

  Fly   300 EC 301
            :|
Human   313 KC 314

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17192	NP_651522.1	Lipase	55..333	CDD:278576	89/262 (34%)
CG17192	NP_651522.1	Pancreat_lipase_like	62..329	CDD:238363	89/262 (34%)
PNLIPRP1	NP_001290064.1	Lipase	18..353	CDD:278576	89/262 (34%)
		Pancreat_lipase_like	52..349	CDD:238363	89/262 (34%)
		PLAT_PL	356..467	CDD:238857
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145290
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.940