Protein Alignment CG17192 and PNLIP

DIOPT Version :10

• Sequence 1: NP_651522.1
• Gene: CG17192 / 43248
• FlyBaseID: FBgn0039472
• Length: 337
• Species: Drosophila melanogaster
• Sequence 2: NP_000927.1
• Gene: PNLIP / 5406
• HGNCID: 9155
• Length: 465
• Species: Homo sapiens
• Alignment Length: 326
• Identity: 98/326 - (30%)
• Similarity: 147/326 - (45%)
• Gaps: 38/326 - (11%)

  Fly     1 MRELFFLAALL--VAGNALPIEERINGENGWFVPQEDGTFQWMDKKDAKELLENISPLEFRSNEV 63
            |..|:.|:.||  |||..: ..||:    |.|  .:|..:..:.::..     :|.|...:....
Human     1 MLPLWTLSLLLGAVAGKEV-CYERL----GCF--SDDSPWSGITERPL-----HILPWSPKDVNT 53

  Fly    64 SFYLYTKQNPTEGQEITADASSIVASHFNKDHGTRFVIHGWKGKYTDSMNVDITKAWLSKGDFNV 128
            .|.|||.:||...||:.||:|||..|:|..:..|||:|||:..|..::...::.|........|.
Human    54 RFLLYTNENPNNFQEVAADSSSISGSNFKTNRKTRFIIHGFIDKGEENWLANVCKNLFKVESVNC 118

  Fly   129 IVVNWARSQSVDYAMSVRAVPGAGTKVGEMIQYMHENHDMSLETLEVIGHSLGAHVAGYAGKQVG 193
            |.|:|.......|..:.:.:...|.:|...::::......|...:.|||||||||.||.||::.
Human   119 ICVDWKGGSRTGYTQASQNIRIVGAEVAYFVEFLQSAFGYSPSNVHVIGHSLGAHAAGEAGRRT- 182

  Fly   194 QKRVHTIVGLDPALPLFSYDNPDKRLSSEDAFYVESIQTNGGV------KGFVKPIGKAAFYVSG 252
            ...:..|.|||||.|.|.......||...||.:|:.|.|:|..      .|..:.:|...|:.:|
Human   183 NGTIGRITGLDPAEPCFQGTPELVRLDPSDAKFVDVIHTDGAPIVPNLGFGMSQVVGHLDFFPNG 247

  Fly   253 GRKQPGCG-------VDLAG---------TCSHARSVIYYAEAITE-NSFGAIQCQDYQAALDNE 300
            |.:.|||.       ||:.|         .|:|.||..||.::|.. :.|....|..|.....|:
Human   248 GVEMPGCKKNILSQIVDIDGIWEGTRDFAACNHLRSYKYYTDSIVNPDGFAGFPCASYNVFTANK 312

  Fly   301 C 301
            |
Human   313 C 313

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17192	NP_651522.1	Pancreat_lipase_like	62..329	CDD:238363	83/263 (32%)
PNLIP	NP_000927.1	Lipase	17..352	CDD:395099	90/310 (29%)
		PLAT_PL	355..465	CDD:238857