DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17192 and lipca

DIOPT Version :9

Sequence 1:	NP_651522.1	Gene:	CG17192 / 43248	FlyBaseID:	FBgn0039472	Length:	337	Species:	Drosophila melanogaster
Sequence 2:	NP_957316.1	Gene:	lipca / 393997	ZFINID:	ZDB-GENE-040426-1361	Length:	514	Species:	Danio rerio

Alignment Length:	323	Identity:	82/323 - (25%)
Similarity:	132/323 - (40%)	Gaps:	74/323 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    65 FYLYTKQNPTEG-------QEITADASSIVASHFNKDHGTRFVIHGWKGKYTDSMNVD-ITKAWL 121
            |.:||....||.       |..|.||..     ||.......:||||        :|| :.:.|:
Zfish    46 FRVYTDGEYTEDTCALELFQPHTLDACG-----FNSSLPLAIIIHGW--------SVDGMMEKWI 97

  Fly   122 SK---------GDFNVIVVNWARSQSVDYAMSVRAVPGAGTKVGEMIQYMHENHDMSLETLEVIG 177
            |:         |:.||::.:|.......|.::.:.....|..:..::.::.:.....|..:.:||
Zfish    98 SRLASALKSSEGNINVLIADWLTLAHQHYPIAAQNTRIVGQDIAHLLSWLEDFKQFPLGKVHLIG 162

  Fly   178 HSLGAHVAGYAGKQVGQ--KRVHTIVGLDPALPLFSYDNPDKRLSSEDAFYVESIQT-----NGG 235
            :|||||::|:||..:..  :.:..|.|||||.|:|...:...|||.|||.:|::|.|     .|.
Zfish   163 YSLGAHISGFAGSNLAMSGRTLGRITGLDPAGPMFEGMSHTDRLSPEDAKFVDAIHTFTLQRMGL 227

  Fly   236 VKGFVKPIGKAAFYVSGGRKQPGC-----------------GVDLAGTCSHARSVIYYAEAI--T 281
            ..|..:|:....||.:||..||||                 |.:....|:|.|:|..:.:::  .
Zfish   228 SVGIKQPVAHFDFYPNGGSFQPGCQLHMQNIYAHLAQHGIMGFEQTVKCAHERAVHLFIDSLLNK 292

  Fly   282 ENSFGAIQCQDYQA-----ALD---NEC---GSSFSSVRMAEDTNAYNVEGHFYVPVNSEAPF 333
            :....|.:|.|..|     .||   |.|   |.....||..:..       ..::...|..|:
Zfish   293 DKQIMAYKCSDNTAFDKGNCLDCRKNRCNTLGYDIKKVRTGKSK-------RLFLKTRSHMPY 348

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17192	NP_651522.1	Lipase	55..333	CDD:278576	81/321 (25%)
CG17192	NP_651522.1	Pancreat_lipase_like	62..329	CDD:238363	80/317 (25%)
lipca	NP_957316.1	lipo_lipase	44..488	CDD:132274	82/323 (25%)
		Pancreat_lipase_like	54..344	CDD:238363	77/309 (25%)
		PLAT_LPL	351..485	CDD:238856
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170578576
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.940