DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17192 and Lipg

DIOPT Version :9

Sequence 1:	NP_651522.1	Gene:	CG17192 / 43248	FlyBaseID:	FBgn0039472	Length:	337	Species:	Drosophila melanogaster
Sequence 2:	NP_001012759.1	Gene:	Lipg / 291437	RGDID:	1310740	Length:	493	Species:	Rattus norvegicus

Alignment Length:	315	Identity:	95/315 - (30%)
Similarity:	151/315 - (47%)	Gaps:	63/315 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    63 VSFYLYTKQNPT-EGQEITADASSIVAS-HFNKDHGTRFVIHGW--KGKYTDSMNVDITKAWLSK 123
            |:|.:.|.::|. ||..::...|.::.: .||....|.|:||||  .|.:         ::||.|
  Rat    51 VTFNIRTSKDPEHEGCNLSLGDSKLLENCGFNMTAKTFFIIHGWTMSGMF---------ESWLHK 106

  Fly   124 ---------GDFNVIVVNW---ARSQSVDYAMSVRAVPGAGTKVGEMIQYMHENHDMSLETLEVI 176
                     .:.||:||:|   |....:|...:.|.|   |.:|..|:.::.|..:.||..:.:|
  Rat   107 LVSALQTREKEANVVVVDWLPLAHQLYIDAVSNTRVV---GRRVAGMLNWLQEKGEFSLGDVHLI 168

  Fly   177 GHSLGAHVAGYAGKQVGQKRVHTIVGLDPALPLFSYDNPDKRLSSEDAFYVESIQT---NGGVK- 237
            |:|||||||||||..| :..|..|.|||||.|:|...:.::|||.:||.:|:.:.|   :.|:.
  Rat   169 GYSLGAHVAGYAGNFV-KGTVGRITGLDPAGPMFEGVDINRRLSPDDADFVDVLHTYTLSFGLSI 232

  Fly   238 GFVKPIGKAAFYVSGGRKQPGCGV-DLAGT-----------CSHARSVIYYAEAITEN---SFGA 287
            |...|:|....|.:||..|||||. |:.|:           |.|.|:|..:.:::...   || |
  Rat   233 GIRMPVGHIDIYPNGGDFQPGCGFNDVMGSFAYGTISEMVKCEHERAVHLFVDSLVNQDKPSF-A 296

  Fly   288 IQCQDYQ--------AALDNECGS-SFSSVRMAEDTNAYNVEGHFYVPVNSEAPF 333
            .||.|..        :...|.|.: .:::.:|.:..|:     ..|:...:..||
  Rat   297 FQCTDPNRFKRGICLSCRKNRCNNIGYNAKKMRKKRNS-----KMYLKTRAGMPF 346

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17192	NP_651522.1	Lipase	55..333	CDD:278576	93/313 (30%)
CG17192	NP_651522.1	Pancreat_lipase_like	62..329	CDD:238363	93/309 (30%)
Lipg	NP_001012759.1	Pancreat_lipase_like	51..342	CDD:238363	93/309 (30%)
		lipo_lipase	53..488	CDD:132274	94/313 (30%)
		Heparin-binding. /evidence=ECO:0000250	327..339		3/16 (19%)
		PLAT_LPL	349..485	CDD:238856
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166338932
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.940