DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17192 and Pnliprp2

DIOPT Version :9

Sequence 1:	NP_651522.1	Gene:	CG17192 / 43248	FlyBaseID:	FBgn0039472	Length:	337	Species:	Drosophila melanogaster
Sequence 2:	NP_035258.2	Gene:	Pnliprp2 / 18947	MGIID:	1336202	Length:	482	Species:	Mus musculus

Alignment Length:	322	Identity:	100/322 - (31%)
Similarity:	151/322 - (46%)	Gaps:	34/322 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 LFFLAALLVAGNALPIEERINGENGWFVPQEDGTFQWMDKKDAKELLENISPLEFRSNEVSFYLY 68
            |.:|.:||:|  .:..:|...|..|.|  ..|..:..|.::.:|     |.|......:..|.||
Mouse    17 LCWLVSLLLA--TVGGKEVCYGHLGCF--SNDKPWAGMIQRPSK-----IFPWSPEDIDTRFLLY 72

  Fly    69 TKQNPTEGQEITA-DASSIVASHFNKDHGTRFVIHGWKGKYTDSMNVDITKAWLSKGDFNVIVVN 132
            |.:||...|.|:| |.::|.||:|..|..|||:|||:..|..:...:|:.|........|.|.|:
Mouse    73 TNENPNNYQIISATDPATINASNFQLDRKTRFIIHGFIDKGEEGWLLDMCKKMFQVEKVNCICVD 137

  Fly   133 WARSQSVDYAMSVRAVPGAGTKVGEMIQYMHENHDMSLETLEVIGHSLGAHVAGYAGKQVGQKRV 197
            |.|....:|..:.......|.::..::|.:......|.|.:.:||||||:||||.||::: :..|
Mouse   138 WKRGSRTEYTQASYNTRVVGAEIAFLVQVLSTEMGYSPENVHLIGHSLGSHVAGEAGRRL-EGHV 201

  Fly   198 HTIVGLDPALPLFSYDNPDKRLSSEDAFYVESIQTNGGV------KGFVKPIGKAAFYVSGGRKQ 256
            ..|.|||||.|.|.....:.||...||.:|:.|.|:...      .|..:.:|...|:.:||::.
Mouse   202 GRITGLDPAEPCFQGLPEEVRLDPSDAMFVDVIHTDSAPIIPYLGFGMSQKVGHLDFFPNGGKEM 266

  Fly   257 PGCG-------VDLAG---------TCSHARSVIYYAEAI-TENSFGAIQCQDYQAALDNEC 301
            |||.       ||:.|         .|:|.||..|||.:| ..:.|....|..|:....|:|
Mouse   267 PGCQKNILSTIVDINGIWEGTRNFAACNHLRSYKYYASSILNPDGFLGYPCSSYEKFQHNDC 328

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17192	NP_651522.1	Lipase	55..333	CDD:278576	87/271 (32%)
CG17192	NP_651522.1	Pancreat_lipase_like	62..329	CDD:238363	86/264 (33%)
Pnliprp2	NP_035258.2	Lipase	31..367	CDD:278576	95/306 (31%)
		Pancreat_lipase_like	65..363	CDD:238363	86/265 (32%)
		Required for galactolipase activity. /evidence=ECO:0000250\|UniProtKB:P54317	106..118		4/11 (36%)
		Required for galactolipase activity. /evidence=ECO:0000250\|UniProtKB:P54317	270..292		3/21 (14%)
		PLAT_PL	370..482	CDD:238857
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167835375
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.940