DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6295 and lipca

DIOPT Version :9

Sequence 1:	NP_651521.1	Gene:	CG6295 / 43247	FlyBaseID:	FBgn0039471	Length:	338	Species:	Drosophila melanogaster
Sequence 2:	NP_957316.1	Gene:	lipca / 393997	ZFINID:	ZDB-GENE-040426-1361	Length:	514	Species:	Danio rerio

Alignment Length:	386	Identity:	101/386 - (26%)
Similarity:	158/386 - (40%)	Gaps:	91/386 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 MKLFLALAFCVLAANAVEVRVNGENGWYVPQADGTMEWMDREFAEAYLETKNRMEGRNVLNPVTF 66
            ||..:.:..|.|..:.:              .||.....:|...|.....|.|.|.::|     |
Zfish     1 MKTLIKIVLCFLMISQL--------------TDGATFQGNRADTEPEARMKMRYEPKSV-----F 46

  Fly    67 YLYTNSNRNSPQEIKATSA-------SISGSHFNPNHPTRFTIHGWSSSKDEFINYGVRDAWF-- 122
            .:||:.     :..:.|.|       ::....||.:.|....|||||..       |:.:.|.
Zfish    47 RVYTDG-----EYTEDTCALELFQPHTLDACGFNSSLPLAIIIHGWSVD-------GMMEKWISR 99

  Fly   123 -------THGDMNMIAVDWGRARSVDYASSVLAVPGVGEQVATLINFMRSNHGLNLDNTMVIGHS 180
                   :.|::|::..||.......|..:......||:.:|.|::::.......|....:||:|
Zfish   100 LASALKSSEGNINVLIADWLTLAHQHYPIAAQNTRIVGQDIAHLLSWLEDFKQFPLGKVHLIGYS 164

  Fly   181 LGAHVSGYAGKNV-KNGQ-LHTIIGLDPALPLFSYDSPNKRLSSTDAYYVESIQT-----NGGTL 238
            ||||:||:||.|: .:|: |..|.|||||.|:|...|...|||..||.:|::|.|     .|.::
Zfish   165 LGAHISGFAGSNLAMSGRTLGRITGLDPAGPMFEGMSHTDRLSPEDAKFVDAIHTFTLQRMGLSV 229

  Fly   239 GFLKPIGKGAFYPNGGKSQPGC-----------------GVDLTGSCAHSRSVIYYAESVTENNF 286
            |..:|:....||||||..||||                 |.:.|..|||.|:|..:.:|:...:.
Zfish   230 GIKQPVAHFDFYPNGGSFQPGCQLHMQNIYAHLAQHGIMGFEQTVKCAHERAVHLFIDSLLNKDK 294

  Fly   287 PTM--RCGD---YEEAVAKEC--------GSSYSSVRMGATTNAYMVAGDYYVPVRSDAPY 334
            ..|  :|.|   :::....:|        |.....||.|.:...::       ..||..||
Zfish   295 QIMAYKCSDNTAFDKGNCLDCRKNRCNTLGYDIKKVRTGKSKRLFL-------KTRSHMPY 348

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6295	NP_651521.1	Pancreat_lipase_like	64..330	CDD:238363	85/318 (27%)
lipca	NP_957316.1	lipo_lipase	44..488	CDD:132274	90/329 (27%)
		Pancreat_lipase_like	54..344	CDD:238363	82/303 (27%)
		PLAT_LPL	351..485	CDD:238856
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170578572
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28N19
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.840