DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6295 and Lipg

DIOPT Version :9

Sequence 1:	NP_651521.1	Gene:	CG6295 / 43247	FlyBaseID:	FBgn0039471	Length:	338	Species:	Drosophila melanogaster
Sequence 2:	NP_001012759.1	Gene:	Lipg / 291437	RGDID:	1310740	Length:	493	Species:	Rattus norvegicus

Alignment Length:	313	Identity:	94/313 - (30%)
Similarity:	147/313 - (46%)	Gaps:	59/313 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    64 VTFYLYTNSNRNSPQEIKATSASISGSH------FNPNHPTRFTIHGWSSSKDEFINYGVRDAWF 122
            |||.:.|:.:    .|.:..:.|:..|.      ||....|.|.||||:.|       |:.::|.
  Rat    51 VTFNIRTSKD----PEHEGCNLSLGDSKLLENCGFNMTAKTFFIIHGWTMS-------GMFESWL 104

  Fly   123 ---------THGDMNMIAVDWGRARSVDYASSVLAVPGVGEQVATLINFMRSNHGLNLDNTMVIG 178
                     ...:.|::.|||.......|..:|.....||.:||.::|:::.....:|.:..:||
  Rat   105 HKLVSALQTREKEANVVVVDWLPLAHQLYIDAVSNTRVVGRRVAGMLNWLQEKGEFSLGDVHLIG 169

  Fly   179 HSLGAHVSGYAGKNVKNGQLHTIIGLDPALPLFSYDSPNKRLSSTDAYYVESIQTN----GGTLG 239
            :||||||:||||..|| |.:..|.|||||.|:|.....|:|||..||.:|:.:.|.    |.::|
  Rat   170 YSLGAHVAGYAGNFVK-GTVGRITGLDPAGPMFEGVDINRRLSPDDADFVDVLHTYTLSFGLSIG 233

  Fly   240 FLKPIGKGAFYPNGGKSQPGCGV-DLTGS-----------CAHSRSVIYYAESVTENNFPT--MR 290
            ...|:|....|||||..|||||. |:.||           |.|.|:|..:.:|:...:.|:  .:
  Rat   234 IRMPVGHIDIYPNGGDFQPGCGFNDVMGSFAYGTISEMVKCEHERAVHLFVDSLVNQDKPSFAFQ 298

  Fly   291 CGD---YEEAVAKECGSS------YSSVRMGATTNAYMVAGDYYVPVRSDAPY 334
            |.|   ::..:...|..:      |::.:|....|:.|     |:..|:..|:
  Rat   299 CTDPNRFKRGICLSCRKNRCNNIGYNAKKMRKKRNSKM-----YLKTRAGMPF 346

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6295	NP_651521.1	Pancreat_lipase_like	64..330	CDD:238363	92/307 (30%)
Lipg	NP_001012759.1	Pancreat_lipase_like	51..342	CDD:238363	92/307 (30%)
		lipo_lipase	53..488	CDD:132274	92/311 (30%)
		Heparin-binding. /evidence=ECO:0000250	327..339		4/16 (25%)
		PLAT_LPL	349..485	CDD:238856
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166338930
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.940