DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6295 and PNLIPRP3

DIOPT Version :9

Sequence 1:	NP_651521.1	Gene:	CG6295 / 43247	FlyBaseID:	FBgn0039471	Length:	338	Species:	Drosophila melanogaster
Sequence 2:	NP_001011709.2	Gene:	PNLIPRP3 / 119548	HGNCID:	23492	Length:	467	Species:	Homo sapiens

Alignment Length:	262	Identity:	87/262 - (33%)
Similarity:	118/262 - (45%)	Gaps:	30/262 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    66 FYLYTNSNRNSPQEIKA-TSASISGSHFNPNHPTRFTIHGWSSSKDEFINYGVRDAWFTHGDMNM 129
            |.|||..|.|:.|||.| .|::|..|:|..:..||..|.||.:  |......:.:......|:|.
Human    56 FLLYTIHNPNAYQEISAVNSSTIQASYFGTDKITRINIAGWKT--DGKWQRDMCNVLLQLEDINC 118

  Fly   130 IAVDWGRARSVDYASSVLAVPGVGEQVATLINFMRSNHGLNLDNTMVIGHSLGAHVSGYAGKNVK 194
            |.:||... |.:|..:|..:..||.:||..|:.:......:.....:||||||||::|.||..:.
Human   119 INLDWING-SREYIHAVNNLRVVGAEVAYFIDVLMKKFEYSPSKVHLIGHSLGAHLAGEAGSRIP 182

  Fly   195 NGQLHTIIGLDPALPLFSYDSPNKRLSSTDAYYVESIQTNGGTL------GFLKPIGKGAFYPNG 253
            .  |..|.|||||.|.|.......||..:||.:|:.|.||...:      |.:...|...|||||
Human   183 G--LGRITGLDPAGPFFHNTPKEVRLDPSDANFVDVIHTNAARILFELGVGTIDACGHLDFYPNG 245

  Fly   254 GKSQPGCGVDLTG-----------------SCAHSRSVIYYAESV-TENNFPTMRCGDYEEAVAK 300
            ||..|||...:|.                 .|.|:||..:||||: ..:.|....|..|....|.
Human   246 GKHMPGCEDLITPLLKFNFNAYKKEMASFFDCNHARSYQFYAESILNPDAFIAYPCRSYTSFKAG 310

  Fly   301 EC 302
            .|
Human   311 NC 312

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6295	NP_651521.1	Pancreat_lipase_like	64..330	CDD:238363	87/262 (33%)
PNLIPRP3	NP_001011709.2	Lipase	18..352	CDD:278576	87/262 (33%)
		Pancreat_lipase_like	52..348	CDD:238363	87/262 (33%)
		PLAT_PL	355..467	CDD:238857
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145253
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28N19
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.840