Protein Alignment CG6296 and PNLIPRP2

DIOPT Version :9

• Sequence 1: NP_651520.1
• Gene: CG6296 / 43246
• FlyBaseID: FBgn0039470
• Length: 676
• Species: Drosophila melanogaster
• Sequence 2: NP_005387.3
• Gene: PNLIPRP2 / 5408
• HGNCID: 9157
• Length: 469
• Species: Homo sapiens
• Alignment Length: 416
• Identity: 114/416 - (27%)
• Similarity: 174/416 - (41%)
• Gaps: 75/416 - (18%)

  Fly    73 FYLYTLQNPSTGQQIKATQ-DSIDGSFFNPQNPTRITIHGWNSNYKDGVNTRVADAWFQYGDYNM 136
            |.|||.:||:..|.|..|: |:|:.|.|.....||..|||:....:|...:.:....|:....|.
Human    56 FLLYTNENPNNFQLITGTEPDTIEASNFQLDRKTRFIIHGFLDKAEDSWPSDMCKKMFEVEKVNC 120

  Fly   137 IAVDWLRGRSLEYASSVAGAPGAGKKVAALVDFLVEGYGMSLDTLEIVGFSLGAHVAGHTAKQVN 201
            |.|||..|....|..:|......|.:.|.|:..|....|.||:.:.::|.|||||.|....:::
Human   121 ICVDWRHGSRAMYTQAVQNIRVVGAETAFLIQALSTQLGYSLEDVHVIGHSLGAHTAAEAGRRL- 184

  Fly   202 SGKVGKVVGLDPASPLISYSNTEKRLSSDDALYVESIQTNGA----ILGFG--QPIGKASFYMNG 260
            .|:||::.|||||.|.......|.||...||::|:.|.|:.:    .||||  |.:|...|:.||
Human   185 GGRVGRITGLDPAGPCFQDEPEEVRLDPSDAVFVDVIHTDSSPIVPSLGFGMSQKVGHLDFFPNG 249

  Fly   261 GRSQPGCG-------IDITG---------SCSHTKAVLYYVEALL-WNNFPSIKCESSVDANKNN 308
            |:..|||.       .||.|         ||:|.::..||..::| .:.|....|.|..:..::.
Human   250 GKEMPGCKKNVLSTITDIDGIWEGIGGFVSCNHLRSFEYYSSSVLNPDGFLGYPCASYDEFQESK 314

  Fly   309 C-----------GNTYSSVFMGASINFFVAEGIFYVPVNKES-----PYGLGELNSGGEATTGTP 357
            |           |: |:..|.|.:   ...|..|::...:..     .|.:....||.|...|..
Human   315 CFPCPAEGCPKMGH-YADQFKGKT---SAVEQTFFLNTGESGNFTSWRYKVSVTLSGKEKVNGYI 375

  Fly   358 EITSTTVDGEDESTTEVSTSTTTDKPEESTTEEPEEDSTTNGKPEE------------------- 403
            .|   .:.|.:|::.:......:.||:.|.|...:.|... ||.::
Human   376 RI---ALYGSNENSKQYEIFKGSLKPDASHTCAIDVDFNV-GKIQKVKFLWNKRGINLSEPKLGA 436

  Fly   404 SSTTTEQPED-------STTTTEEPI 422
            |..|.:..||       |:.|.||.:
Human   437 SQITVQSGEDGTEYNFCSSDTVEENV 462

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6296	NP_651520.1	Pancreat_lipase_like	71..337	CDD:238363	91/298 (31%)
PNLIPRP2	NP_005387.3	Lipase	18..354	CDD:395099	91/302 (30%)
		Required for galactolipase activity. /evidence=ECO:0000269|PubMed:26494624	93..105		4/11 (36%)
		Required for galactolipase activity. /evidence=ECO:0000269|PubMed:26494624	257..279		3/21 (14%)
		PLAT_PL	357..469	CDD:238857	23/110 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145301
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.940