Protein Alignment CG6296 and PNLIP

DIOPT Version :9

• Sequence 1: NP_651520.1
• Gene: CG6296 / 43246
• FlyBaseID: FBgn0039470
• Length: 676
• Species: Drosophila melanogaster
• Sequence 2: NP_000927.1
• Gene: PNLIP / 5406
• HGNCID: 9155
• Length: 465
• Species: Homo sapiens
• Alignment Length: 451
• Identity: 124/451 - (27%)
• Similarity: 177/451 - (39%)
• Gaps: 101/451 - (22%)

  Fly    67 STNTVN--FYLYTLQNPSTGQQIKATQDSIDGSFFNPQNPTRITIHGWNSNYKDGVNTRVADAWF 129
            |...||  |.|||.:||:..|::.|...||.||.|.....||..|||:....::.....|....|
Human    47 SPKDVNTRFLLYTNENPNNFQEVAADSSSISGSNFKTNRKTRFIIHGFIDKGEENWLANVCKNLF 111

  Fly   130 QYGDYNMIAVDWLRGRSLEYASSVAGAPGAGKKVAALVDFLVEGYGMSLDTLEIVGFSLGAHVAG 194
            :....|.|.|||..|....|..:.......|.:||..|:||...:|.|...:.::|.|||||.||
Human   112 KVESVNCICVDWKGGSRTGYTQASQNIRIVGAEVAYFVEFLQSAFGYSPSNVHVIGHSLGAHAAG 176

  Fly   195 HTAKQVNSGKVGKVVGLDPASPLISYSNTEKRLSSDDALYVESIQTNGA----ILGFG--QPIGK 253
            ...::.| |.:|::.|||||.|....:....||...||.:|:.|.|:||    .||||  |.:|.
Human   177 EAGRRTN-GTIGRITGLDPAEPCFQGTPELVRLDPSDAKFVDVIHTDGAPIVPNLGFGMSQVVGH 240

  Fly   254 ASFYMNGGRSQPGCG-------IDITG---------SCSHTKAVLYYVEALL-WNNFPSIKCESS 301
            ..|:.|||...|||.       :||.|         :|:|.::..||.:::: .:.|....|
Human   241 LDFFPNGGVEMPGCKKNILSQIVDIDGIWEGTRDFAACNHLRSYKYYTDSIVNPDGFAGFPC--- 302

  Fly   302 VDANKNNCGNTYSSVFMGASINFFVAEGIFYVPVNKESPYG------LGELNSGGE---ATTGTP 357
                              ||.|.|.|...|..|.......|      .|:.|..|:   ..||..
Human   303 ------------------ASYNVFTANKCFPCPSGGCPQMGHYADRYPGKTNDVGQKFYLDTGDA 349

  Fly   358 E-------ITSTTVDGEDESTTEVSTSTTTDKPEESTTEEPEEDSTTNGKPEESSTTTEQPEDST 415
            .       ..|.|:.|: :.|..:..|...:|              .|.|..|....|.:| |||
Human   350 SNFARWRYKVSVTLSGK-KVTGHILVSLFGNK--------------GNSKQYEIFKGTLKP-DST 398

  Fly   416 TTTEEPIDSTTEAPEDE-------STTSSP-------------TDGGEQSTTEEPETTTEK 456
            .:.|  .||..:..:.:       :...:|             |:.|:|.....|||..|:
Human   399 HSNE--FDSDVDVGDLQMVKFIWYNNVINPTLPRVGASKIIVETNVGKQFNFCSPETVREE 457

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6296	NP_651520.1	Pancreat_lipase_like	71..337	CDD:238363	92/290 (32%)
PNLIP	NP_000927.1	Lipase	17..352	CDD:278576	99/326 (30%)
		PLAT_PL	355..465	CDD:238857	25/121 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145321
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28N19
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.840