DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6296 and lpl

DIOPT Version :9

Sequence 1:	NP_651520.1	Gene:	CG6296 / 43246	FlyBaseID:	FBgn0039470	Length:	676	Species:	Drosophila melanogaster
Sequence 2:	NP_571202.1	Gene:	lpl / 30354	ZFINID:	ZDB-GENE-990415-139	Length:	511	Species:	Danio rerio

Alignment Length:	268	Identity:	82/268 - (30%)
Similarity:	122/268 - (45%)	Gaps:	37/268 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    73 FYLYTLQNPS-------TGQQIKATQDSIDGSFFNPQNPTRITIHGW--NSNYKDGVNTRVADAW 128
            |...||:.|.       .||     ..||....||.:..|.|.||||  ...::..|...|...:
Zfish    60 FSFRTLEEPEDDLCYIVPGQ-----PQSIKDCNFNTETKTFIVIHGWTVTGMFESWVPKLVTALY 119

  Fly   129 FQYGDYNMIAVDWLRGRSLEYASSVAGAPGAGKKVAALVDFLVEGYGMSLDTLEIVGFSLGAHVA 193
            .:....|:|.||||......|.:|.:.....||.||..|::|........:.|.::|:|||||||
Zfish   120 EREPSANVIVVDWLSRAQQHYPTSASYTKLVGKDVAKFVNWLQAEIDYPWEKLHLLGYSLGAHVA 184

  Fly   194 GHTAKQVNSGKVGKVVGLDPASPLISYSNTEKRLSSDDALYVESIQTN-----GAILGFGQPIGK 253
            | .|..:...||.::.|:|||.|...|:::...||.|||.:|:.:.||     ...:|..:|:|.
Zfish   185 G-IAGLLTKHKVNRITGMDPAGPTFEYADSLSTLSPDDANFVDVLHTNTRGSPDRSIGIQRPVGH 248

  Fly   254 ASFYMNGGRSQPGCGID-------ITG--------SCSHTKAVLYYVEALLWNNFPSI--KCESS 301
            ...|.|||..||||.:.       .||        .|||.:::..::::|:..:..|:  :|.|.
Zfish   249 IDIYPNGGTFQPGCDLQNTMLMVATTGLRNMDQIVKCSHERSIHLFIDSLVNQDHESMAFRCSSR 313

  Fly   302 VDANKNNC 309
            ...||..|
Zfish   314 DSFNKGMC 321

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6296	NP_651520.1	Pancreat_lipase_like	71..337	CDD:238363	82/268 (31%)
lpl	NP_571202.1	lipo_lipase	52..492	CDD:132274	82/268 (31%)
		Pancreat_lipase_like	56..353	CDD:238363	82/268 (31%)
		PLAT	360..484	CDD:294016
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170578598
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.940