DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6296 and Lipg

DIOPT Version :9

Sequence 1:	NP_651520.1	Gene:	CG6296 / 43246	FlyBaseID:	FBgn0039470	Length:	676	Species:	Drosophila melanogaster
Sequence 2:	NP_034850.3	Gene:	Lipg / 16891	MGIID:	1341803	Length:	500	Species:	Mus musculus

Alignment Length:	273	Identity:	85/273 - (31%)
Similarity:	129/273 - (47%)	Gaps:	43/273 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    81 PSTGQQIKATQDS--------------IDGSFFNPQNPTRITIHGWNSN--YKDGVNTRVADAWF 129
            ||....|:.::|.              ::...||....|...||||..:  ::..::..|:....
Mouse    47 PSVAFNIRTSKDPEQEGCNLSLGDSKLLENCGFNMTAKTFFIIHGWTMSGMFESWLHKLVSALQM 111

  Fly   130 QYGDYNMIAVDWLRGRSLEYASSVAGAPGAGKKVAALVDFLVEGYGMSLDTLEIVGFSLGAHVAG 194
            :..|.|::.||||......|..:|......|::||.::|:|.|....||..:.::|:||||||||
Mouse   112 REKDANVVVVDWLPLAHQLYTDAVNNTRVVGQRVAGMLDWLQEKEEFSLGNVHLIGYSLGAHVAG 176

  Fly   195 HTAKQVNSGKVGKVVGLDPASPLISYSNTEKRLSSDDALYVESIQTN----GAILGFGQPIGKAS 255
            :....| .|.||::.|||||.|:....:..:|||.|||.:|:.:.|.    |..:|...|:|...
Mouse   177 YAGNFV-KGTVGRITGLDPAGPMFEGVDINRRLSPDDADFVDVLHTYTLSFGLSIGIRMPVGHID 240

  Fly   256 FYMNGGRSQPGCGI-DITGS-----------CSHTKAVLYYVEALLWNNFPS--IKCESS----- 301
            .|.|||..|||||. |:.||           |.|.:||..:|::|:..:.||  .:|..|
Mouse   241 IYPNGGDFQPGCGFNDVIGSFAYGTISEMVKCEHERAVHLFVDSLVNQDKPSFAFQCTDSSRFKR 305

  Fly   302 ---VDANKNNCGN 311
               :...||.|.|
Mouse   306 GICLSCRKNRCNN 318

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6296	NP_651520.1	Pancreat_lipase_like	71..337	CDD:238363	85/273 (31%)
Lipg	NP_034850.3	Pancreat_lipase_like	49..340	CDD:238363	83/271 (31%)
		lipo_lipase	51..485	CDD:132274	83/269 (31%)
		Heparin-binding. /evidence=ECO:0000250	325..337
		PLAT_LPL	347..483	CDD:238856
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167835331
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.940