DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31075 and PUT2

DIOPT Version :9

Sequence 1:	NP_001247324.1	Gene:	CG31075 / 43244	FlyBaseID:	FBgn0051075	Length:	508	Species:	Drosophila melanogaster
Sequence 2:	NP_011902.1	Gene:	PUT2 / 856432	SGDID:	S000001079	Length:	575	Species:	Saccharomyces cerevisiae

Alignment Length:	493	Identity:	136/493 - (27%)
Similarity:	222/493 - (45%)	Gaps:	49/493 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 LFINNEFV-DSVSGKTFATFNPATSKEIV-QVSEGDKADIDLAVKAAKKAFHRDSEWRKLSPLQR 98
            |.||.|.: |:.....|...|||..:::: .|::..:.|:..||||||.|   ..:|..|....|
Yeast    63 LVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDA---KKDWYNLPFYDR 124

  Fly    99 TNLMNKLCALMD---RDKAFLASLETQDNGKPYAEALFD-VTYSILTLQYYAGWTDKFFGD--TI 157
            :.:..|...|:.   |.....|::..|  ||...:|..| :|......:||..:....:..  ..
Yeast   125 SAIFLKAADLISTKYRYDMLAATMLGQ--GKNVYQAEIDCITELSDFFRYYVKYASDLYAQQPVE 187

  Fly   158 PAGGFVSMTRKEPV-GVVGQIIPWNYPLLMLAWKWGPALAVGCTIIMKPAEQTPLTALHMAALAK 221
            .|.|..:.....|: |.|..:.|:|:..:.......||| :|.|::.||::...|:...:..:.:
Yeast   188 SADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPAL-MGNTVVWKPSQTAALSNYLLMTVLE 251

  Fly   222 EAGFPAGVINVVNGFGPTAGAAISAHPDIAKVAFTGSVEI-----GRIVMQAAATS----NLKRV 277
            |||.|.||||.:.|........:.|..|...:.||||..:     |:|  |:....    :..|:
Yeast   252 EAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGKI--QSGVVEGKYRDYPRI 314

  Fly   278 SLELGGKSPVVVFDDADIDFAVETTHEALFSNHGQSCCAGSRTYVHEKIYDEFVAKAAAKAKARK 342
            ..|.|||:..:|...|:|..||.:|....|...||.|.|.||.|:.|...:||::......:::.
Yeast   315 IGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRLYLPESKSEEFLSDMFGILQSQN 379

  Fly   343 V------GNPFE-QNVQ--QGPQIDDDMLTKVLGYIESGKKE-GAKLQAGGKRIGNVGFFVEPTV 397
            |      .:|.. .|::  .||.|.:....|::..||..||: ..::..||:...:.|:||.|||
Yeast   380 VVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIEDAKKDPELEILYGGQYDKSQGWFVGPTV 444

  Fly   398 FSDVKDDMRIAQEEIFGPVQSIFKFSSLE-----EMIDRANNVQYGLAAGVITNDINKALKFAN- 456
            ....:.|......|.|||:.:::::...|     ::||  |..||.|...:...| .||:::|:
Yeast   445 IKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEICDIID--NTSQYALTGAIFAKD-RKAIEYADE 506

  Fly   457 --NVDAGSVWIN--CYDAVLPSTPFGGYKHSGIGRELG 490
              ...||:.:||  |..||:....|||.:.||...:.|
Yeast   507 KLKFSAGNFYINDKCTGAVVSQQWFGGARMSGTDDKAG 544

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31075	NP_001247324.1	ALDH-SF	33..506	CDD:299846	136/493 (28%)
PUT2	NP_011902.1	D1pyr5carbox1	29..574	CDD:273517	136/493 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1012
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810