DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31075 and ALDH2B4

DIOPT Version :9

Sequence 1:	NP_001247324.1	Gene:	CG31075 / 43244	FlyBaseID:	FBgn0051075	Length:	508	Species:	Drosophila melanogaster
Sequence 2:	NP_190383.1	Gene:	ALDH2B4 / 823955	AraportID:	AT3G48000	Length:	538	Species:	Arabidopsis thaliana

Alignment Length:	478	Identity:	263/478 - (55%)
Similarity:	343/478 - (71%)	Gaps:	3/478 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 NYCQLFINNEFVDSVSGKTFATFNPATSKEIVQVSEGDKADIDLAVKAAKKAFHRDSEWRKLSPL 96
            ::.||.||..||||.|||||.|.:|.|.:.|..|:|||..||:.|||||:.||. :..|.|:|..
plant    56 SHTQLLINGNFVDSASGKTFPTLDPRTGEVIAHVAEGDAEDINRAVKAARTAFD-EGPWPKMSAY 119

  Fly    97 QRTNLMNKLCALMDRDKAFLASLETQDNGKPYAEAL-FDVTYSILTLQYYAGWTDKFFGDTIPA- 159
            :|:.::.:...|:::....||||||.||||||.::| .::.......:|||||.||..|.||||
plant   120 ERSRVLLRFADLVEKHSEELASLETWDNGKPYQQSLTAEIPMFARLFRYYAGWADKIHGLTIPAD 184

  Fly   160 GGFVSMTRKEPVGVVGQIIPWNYPLLMLAWKWGPALAVGCTIIMKPAEQTPLTALHMAALAKEAG 224
            |.:...|..||:||.|||||||:||||.|||.|||||.|.||::|.||||||||.:...|..|||
plant   185 GNYQVHTLHEPIGVAGQIIPWNFPLLMFAWKVGPALACGNTIVLKTAEQTPLTAFYAGKLFLEAG 249

  Fly   225 FPAGVINVVNGFGPTAGAAISAHPDIAKVAFTGSVEIGRIVMQAAATSNLKRVSLELGGKSPVVV 289
            .|.||:|:|:|||.|||||:::|.|:.|:|||||.:.|::::..||.||||.|:||||||||.:|
plant   250 LPPGVLNIVSGFGATAGAALASHMDVDKLAFTGSTDTGKVILGLAANSNLKPVTLELGGKSPFIV 314

  Fly   290 FDDADIDFAVETTHEALFSNHGQSCCAGSRTYVHEKIYDEFVAKAAAKAKARKVGNPFEQNVQQG 354
            |:|||||.|||..|.|||.|.||.|||||||:||||:|||||.|:.|:|..|.||:||.:.::||
plant   315 FEDADIDKAVELAHFALFFNQGQCCCAGSRTFVHEKVYDEFVEKSKARALKRVVGDPFRKGIEQG 379

  Fly   355 PQIDDDMLTKVLGYIESGKKEGAKLQAGGKRIGNVGFFVEPTVFSDVKDDMRIAQEEIFGPVQSI 419
            ||||.....||:.||:||.:..|.|:.||.:||:.|:|::|||||:|||||.|||:|||||||||
plant   380 PQIDLKQFEKVMKYIKSGIESNATLECGGDQIGDKGYFIQPTVFSNVKDDMLIAQDEIFGPVQSI 444

  Fly   420 FKFSSLEEMIDRANNVQYGLAAGVITNDINKALKFANNVDAGSVWINCYDAVLPSTPFGGYKHSG 484
            .|||.::|:|.|||..:|||||||.|.:::.|.:.:..:.||:||:||:|....:.||||||.||
plant   445 LKFSDVDEVIKRANETKYGLAAGVFTKNLDTANRVSRALKAGTVWVNCFDVFDAAIPFGGYKMSG 509

  Fly   485 IGRELGKDGLDNYLETKTITMKL 507
            .|||.|...|:|||:.|.:...|
plant   510 NGREKGIYSLNNYLQIKAVVTAL 532

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31075	NP_001247324.1	ALDH-SF	33..506	CDD:299846	262/474 (55%)
ALDH2B4	NP_190383.1	PLN02466	1..538	CDD:215259	263/478 (55%)
ALDH2B4	NP_190383.1	ALDH_F2BC	55..530	CDD:143460	262/474 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1012
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53964
OrthoDB	1	1.010	-	-		D153834at2759
OrthoFinder	1	1.000	-	-		FOG0000158
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100163
Panther	1	1.100	-	-	O	PTHR11699
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X158
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	8.830