Protein Alignment CG31075 and ALDH5A1

DIOPT Version :9

• Sequence 1: NP_001247324.1
• Gene: CG31075 / 43244
• FlyBaseID: FBgn0051075
• Length: 508
• Species: Drosophila melanogaster
• Sequence 2: NP_733936.1
• Gene: ALDH5A1 / 7915
• HGNCID: 408
• Length: 548
• Species: Homo sapiens
• Alignment Length: 490
• Identity: 183/490 - (37%)
• Similarity: 273/490 - (55%)
• Gaps: 33/490 - (6%)

  Fly    37 FINNEFVDSVSGKTFATFNPATSKEIVQVSEGDKADIDLAVKAAKKAFHRDSEWRKLSPLQRTNL 101
            |:...::.:.:  ||...:||:...:..|::....:...||:||.:||.|   ||::|..:|::|
Human    64 FVGGRWLPAAA--TFPVQDPASGAALGMVADCGVREARAAVRAAYEAFCR---WREVSAKERSSL 123

  Fly   102 MNKLCALMDRDKAFLASLETQDNGKPYAEALFDVTYSILTLQYYAGWTDKFFGDTI--PAGGFVS 164
            :.|...||.::|..||.:.|.::|||..||..::.||...|::::....:.:||.|  ||....:
Human   124 LRKWYNLMIQNKDDLARIITAESGKPLKEAHGEILYSAFFLEWFSEEARRVYGDIIHTPAKDRRA 188

  Fly   165 MTRKEPVGVVGQIIPWNYPLLMLAWKWGPALAVGCTIIMKPAEQTPLTALHMA------------ 217
            :..|:|:||...|.|||:|..|:..|.|.|||.|||:::||||.||.:||.:|
Human   189 LVLKQPIGVAAVITPWNFPSAMITRKVGAALAAGCTVVVKPAEDTPFSALALAEVNQGFLLDLDP 253

  Fly   218 -ALAKEAGFPAGVINVVNGFGPTA---GAAISAHPDIAKVAFTGSVEIGRIVMQAAATSNLKRVS 278
             .||.:||.|:||.||:......|   |.||...|.::|::||||...|:|::..||.| :||||
Human   254 LLLASQAGIPSGVYNVIPCSRKNAKEVGEAICTDPLVSKISFTGSTTTGKILLHHAANS-VKRVS 317

  Fly   279 LELGGKSPVVVFDDADIDFAVETTHEALFSNHGQSCCAGSRTYVHEKIYDEFV-AKAAAKAKARK 342
            :||||.:|.:|||.|::|.||.....:.|.|.||:|...::..|...|:|.|| |.|.|..|..:
Human   318 MELGGLAPFIVFDSANVDQAVAGAMASKFRNTGQTCVCSNQFLVQRGIHDAFVKAFAEAMKKNLR 382

  Fly   343 VGNPFEQNVQQGPQIDDDMLTKVLGYIESGKKEGAKLQAGGKR--IGNVGFFVEPTVFSDVKDDM 405
            |||.||:...|||.|::..:.||...:.....:||.:..||||  :|. .|| |||:..:|..||
Human   383 VGNGFEEGTTQGPLINEKAVEKVEKQVNDAVSKGATVVTGGKRHQLGK-NFF-EPTLLCNVTQDM 445

  Fly   406 RIAQEEIFGPVQSIFKFSSLEEMIDRANNVQYGLAAGVITNDINKALKFANNVDAGSVWINCYDA 470
            ....||.|||:..:.||.:.||.|..||....|||....:.|..:..:.|..::.|.|.:|  :.
Human   446 LCTHEETFGPLAPVIKFDTEEEAIAIANAADVGLAGYFYSQDPAQIWRVAEQLEVGMVGVN--EG 508

  Fly   471 VLPST--PFGGYKHSGIGRELGKDGLDNYLETKTI 503
            ::.|.  ||||.|.||:|||..|.|:|.|||.|.:
Human   509 LISSVECPFGGVKQSGLGREGSKYGIDEYLELKYV 543

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31075	NP_001247324.1	ALDH-SF	33..506	CDD:299846	183/490 (37%)
ALDH5A1	NP_733936.1	SSADH	78..541	CDD:188167	179/470 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1012
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810